Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4968163 | 0.97 | KMT2A (0.51) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL3480164 | 0.95 | KMT2A (0.51) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL4968951 | 0.95 | KMT2A (0.51) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL3480097 | 0.95 | KMT2A (0.51) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL3479906 | 0.95 | KMT2A (0.51) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL3480058 | 0.95 | KMT2A (0.51) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL3480208 | 0.94 | KMT2A (0.52) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL7702246 | 0.93 | MEN1 (0.48) | MEN1KMT2AMAPK9MAPK10ALDH1A1 | |
| SCHEMBL3479903 | 0.92 | KMT2A (0.53) | MEN1KMT2AALDH1A1GAAPKM | |
| SCHEMBL3479815 | 0.92 | KMT2A (0.54) | MEN1KMT2AALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |