SCHEMBL4970367

SCHEMBL4970367

O=C(O)C#CCCCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.50
RECQL P46063 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPT P10636 2/20 0.50
BLM P54132 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
ALDH1A1 P00352 1/20 0.50
POLB P06746 1/20 0.50
HPGD P15428 1/20 0.50
ALOX12 P18054 1/20 0.50
MCL1 Q07820 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HMGCR P04035 3/20 0.48
LMNA P02545 3/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
TSHR P16473 2/20 0.46
NFKB1 P19838 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4969753 0.93 PTPN7 (0.57) PTPN7RECQLTDP1MAPTBLM
SCHEMBL31520020 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL31520018 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL31520017 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL30966140 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL31520015 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL31520016 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL31520019 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL31520021 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM
SCHEMBL29242822 0.91 PTPN7 (0.61) PTPN7RECQLTDP1MAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912668-A Synthesis of linear aliphatic polyesters 丰益国际有限公司 2025-05-02 CN disclosed
EP-3258929-B1 FACTOR IXA INHIBITORS MERCK SHARP & DOHME (US) 2022-04-27 EP disclosed
US-10351558-B2 Factor IXa inhibitors MERCK SHARP & DOHME CORP. (US) 2019-07-16 US disclosed
US-20180022747-A1 Factor IXa Inhibitors MERCK SHARP & DOHME CORP. (US) 2018-01-25 US disclosed
EP-3258929-A1 FACTOR IXa INHIBITORS Merck Sharp & Dohme Corp. (US) 2017-12-27 EP disclosed
WO-2016133793-A1 FACTOR IXa INHIBITORS MERCK SHARP & DOHME CORP. (US) 2016-08-25 WO disclosed
EP-0980016-B1 ALIGNING AGENT FOR LIQUID CRYSTAL NISSAN CHEMICAL IND LTD (JP) 2008-09-24 EP disclosed
EP-0980016-A1 ALIGNING AGENT FOR LIQUID CRYSTAL Nissan Chemical Industries, Ltd. (JP) 2000-02-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180022747-A1 Factor IXa Inhibitors F9, TFPI, F12 PTPN7 3677/4885RECQL 1467/4885TDP1 4008/4885
US-10351558-B2 Factor IXa inhibitors F9, TFPI, F12 PTPN7 3677/4885RECQL 1467/4885TDP1 4008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.