Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.79 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GALK1 | P51570 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422088 | 0.97 | MAPK9 (0.81) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL2422524 | 0.97 | MAPK9 (0.81) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL4970920 | 0.93 | MAPK9 (0.77) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL2420683 | 0.92 | MAPK9 (0.85) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL2421884 | 0.92 | MAPK9 (0.85) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL2425303 | 0.89 | MAPK9 (0.78) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL2420451 | 0.89 | MAPK9 (0.78) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL1518774 | 0.89 | MAPK9 (1.00) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL6438481 | 0.88 | MAPK9 (0.76) | MAPK9MAPK10GAARXFP1TSHR | |
| SCHEMBL6439255 | 0.88 | MAPK9 (0.76) | MAPK9MAPK10GAARXFP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904181-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007011762-A2 | JNK INHIBITORS FOR THE TREATMENT OF ENDOMETREOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-01-25 | — | — | WO | disclosed |