Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.60 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | CTSH | P09668 | 2/20 | 0.60 |
| ▸ | CTSD | P07339 | 1/20 | 0.60 |
| ▸ | LIN28A | Q9H9Z2 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497311 | 0.90 | CAPN1 (0.51) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL496522 | 0.82 | CAPN1 (0.46) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL497811 | 0.80 | CAPN1 (0.47) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL3326999 | 0.72 | CAPN1 (0.52) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL20094419 | 0.72 | CAPN1 (0.81) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL24185944 | 0.71 | CAPN1 (0.60) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL30668259 | 0.71 | CAPN1 (0.60) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL30668243 | 0.71 | CAPN1 (0.59) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL30668241 | 0.71 | CAPN1 (0.59) | CAPN1CTSBCTSLCTSHCTSD | |
| SCHEMBL24186183 | 0.71 | CAPN1 (0.59) | CAPN1CTSBCTSLCTSHCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106071-B2 | Compositions for treating hyperproliferative vascular disorders and cancers | BIOBUD CO., LTD. (KR) | 2012-01-31 | — | — | US | disclosed |