SCHEMBL497159

SCHEMBL497159

O=P(O)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.60
TSHR P16473 2/20 0.54
FDPS P14324 1/20 0.50
LAP3 P28838 3/20 0.48
ANPEP P15144 2/20 0.48
ACP3 P15309 1/20 0.47
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CFTR P13569 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
POLB P06746 1/20 0.46
ERAP1 Q9NZ08 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8728961 0.88 HPGD (0.65) HPGDTSHRFDPSLAP3ANPEP
SCHEMBL13996805 0.86 HPGD (0.52) HPGDTSHRFDPSLAP3ANPEP
Benzylphosphonic Acid SCHEMBL44318 0.84 HPGD (0.60) HPGDTSHRLAP3ANPEPACP3
SCHEMBL5484404 0.83 CETP (0.53) HPGDTSHR
SCHEMBL17039328 0.83 HPGD (0.48) HPGDTSHRFDPSLAP3ANPEP
Benzylphosphonic Acid SCHEMBL11474641 0.82 HPGD (0.58) HPGDTSHRLAP3ANPEPACP3
SCHEMBL6310521 0.82 HPGD (0.58) HPGDTSHRFDPSLAP3ANPEP
Benzylphosphonic Acid SCHEMBL5332218 0.82 HPGD (0.58) HPGDTSHRLAP3ANPEPACP3
Benzylphosphonic Acid SCHEMBL11339355 0.82 HPGD (0.58) HPGDTSHRLAP3ANPEPACP3
Benzylphosphonic Acid SCHEMBL915222 0.82 HPGD (0.58) HPGDTSHRLAP3ANPEPACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1238423-C Thermoplastic resin composition and molded object thereof POLYPLASTICS CO (JP) 2006-01-25 CN claimed
EP-0567107-B1 Quinoline and quinazoline derivatives for treating arthritis TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-11-21 EP claimed
EP-0608870-B1 Quinoline or quinazoline derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2001-09-05 EP claimed
US-5948782-A ANTIINFLAMMATORY AGENT; RHEUMATIC DISEASES TAKEDA CHEMICAL (JP) 1999-09-07 US claimed
US-5770602-A REACTING QUIONOZOLINE OR QUINOLINE DERIVATIVES CONTAINING LEAVING GROUPS WITH NITROGEN CONTAINING UNSATURATED CYCLIC GROUP WHICH MAY BE SUBSTITUTED OR UNSUBSTITUTED; ANTIARTHRITIC AGENT TAKEDA CHEMICAL INDUSTRIES (JP) 1998-06-23 US claimed
EP-0608870-A1 Quinoline or quinazoline derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-08-03 EP claimed
EP-0567107-A1 Quinoline and quinazoline derivatives for treating arthritis TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-10-27 EP claimed
EP-0196981-B1 PROCESS FOR THE PREPARATION OF COPOLYAMIDES BASED ON HEXAMETHYLENE DIAMINE, APIDIC ACID AND DIMERIC ACID RHONE-POULENC CHIMIE (FR) 1988-10-19 EP claimed
US-4637885-A LUBE OIL, AMINE OR QUATERNARY AMMONIUM SALT OF PHOSPHORIC ACID KAO CORPORATION (JP) 1987-01-20 US claimed
US-4626367-A Water-soluble metal-working lubricant composition KAO CORPORATION (JP) 1986-12-02 US claimed
EP-3500614-B1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING EASTMAN CHEM CO (US) 2025-08-06 EP disclosed
US-11447601-B2 Polyester compositions which comprise tetramethylcyclobutanediol and ethylene glycol for calendering EASTMAN CHEMICAL COMPANY (US) 2022-09-20 US disclosed
US-20190211145-A1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING EASTMAN CHEMICAL COMPANY (US) 2019-07-11 US disclosed
EP-3500614-A1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING Eastman Chemical Company (US) 2019-06-26 EP disclosed
EP-3500544-A1 OIL-SOLUBLE PLANT MICRONUTRIENTS Huntsman Petrochemical LLC (US) 2019-06-26 EP disclosed
EP-0175464-A1 Benzimidazole derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1986-03-26 EP disclosed
EP-0174726-A1 Pyridine derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1986-03-19 EP disclosed
US-4451471-A Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same CIBA-GEIGY CORPORATION (US) 1984-05-29 US disclosed
EP-0061425-A2 Thiazole derivatives, processes for their preparation, medicaments containing them and their use CIBA-GEIGY AG (CH) 1982-09-29 EP disclosed
US-4078016-A Halogenated aromatic polymer/metal phosphinate polymer flame retardant composition CELANESE CORPORATION (US) 1978-03-07 US disclosed