Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973026 | 0.86 | ALOX5AP (0.61) | ALOX5APPTGS1 | |
| SCHEMBL167221 | 0.85 | ALOX5AP (0.61) | ALOX5APPTGS1 | |
| SCHEMBL5530133 | 0.85 | ALOX5AP (0.56) | ALOX5APPTGS1 | |
| SCHEMBL170095 | 0.85 | ALOX5AP (0.77) | ALOX5APPTGS1 | |
| SCHEMBL5530125 | 0.84 | ALOX5AP (0.54) | ALOX5APPTGS1 | |
| SCHEMBL169350 | 0.83 | ALOX5AP (0.73) | ALOX5APPTGS1 | |
| SCHEMBL170114 | 0.79 | ALOX5AP (0.57) | ALOX5APPTGS1 | |
| SCHEMBL5527288 | 0.78 | ALOX5AP (0.51) | ALOX5APPTGS1 | |
| SCHEMBL5527282 | 0.77 | ALOX5AP (0.48) | ALOX5APPTGS1 | |
| SCHEMBL169311 | 0.76 | ALOX5AP (0.78) | ALOX5APPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943219-A2 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | Amira Pharmaceuticals, Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007056021-A2 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | claimed |