⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6908156 | 0.75 | — | — | |
| SCHEMBL2279911 | 0.69 | — | — | |
| SCHEMBL2683 | 0.69 | — | — | |
| Dipyridyl SCHEMBL29351528 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL5922 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL29907716 | 0.67 | KDM4E (1.00) | — | |
| Dipyridyl SCHEMBL3711450 | 0.67 | KDM4E (1.00) | — | |
| SCHEMBL21640917 | 0.67 | — | — | |
| SCHEMBL5862107 | 0.67 | — | — | |
| SCHEMBL28309116 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022189-B1 | 4-(3-CYANOPHENYL)-6-PYRIDINYLPYRIMIDINE MGLU5 MODULATORS | HEPTARES THERAPEUTICS LTD (GB) | 2018-09-26 | — | — | EP | claimed |
| US-9708432-B2 | Highly sensitive (meth)acrylate and radical curable material | AUTONETWORKS TECHNOLOGIES, LTD. (JP) | 2017-07-18 | — | — | US | claimed |
| US-9676745-B2 | 4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators | HEPTARES THERAPEUTICS LIMITED (GB) | 2017-06-13 | — | — | US | claimed |
| US-20160145236-A1 | 4-(3-CYANOPHENYL)-6-PYRIDINYLPYRIMIDINE MGLU5 MODULATORS | NXERA PHARMA UK LIMITED (GB) | 2016-05-26 | — | — | US | claimed |
| EP-3022189-A1 | 4-(3-CYANOPHENYL)-6-PYRIDINYLPYRIMIDINE MGLU5 MODULATORS | Heptares Therapeutics Limited (GB) | 2016-05-25 | — | — | EP | claimed |
| CN-105377832-A | 4- (3-cyanophenyl) -6-pyridylpyrimidine MGLU5 modulators | HEPTARES THERAPEUTICS LTD | 2016-03-02 | — | — | CN | claimed |
| WO-2015008073-A1 | 4-(3-CYANOPHENYL)-6-PYRIDINYLPYRIMIDINE MGLU5 MODULATORS | HEPTARES THERAPEUTICS LIMITED (GB) | 2015-01-22 | — | — | WO | claimed |
| WO-2013167585-A2 | RECYCLING OF ORGANOTIN COMPOUNDS | UNIVERSITEIT ANTWERPEN (BE) | 2013-11-14 | — | — | WO | claimed |
| US-20250388531-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARM INNC (US) | 2025-12-25 | — | — | US | disclosed |
| US-12415795-B2 | 4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators | NXERA PHARMA UK LIMITED (GB) | 2025-09-16 | — | — | US | disclosed |
| WO-2024114765-A1 | BENZOPYRONE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF | 成都地奥九泓制药厂 | 2024-06-06 | — | — | WO | disclosed |
| US-20240139163-A1 | MACROCYCLIC AZOLOPYRIDINE DERIVATIVES AS EED AND PRC2 MODULATORS | Fulcrum Therapeutics, Inc. | 2024-05-02 | — | — | US | disclosed |
| CN-114144230-B | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | 弗尔康医疗公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-115667241-B | Trka inhibitors | 伊莱利利公司 | 2024-04-16 | — | — | CN | disclosed |
| US-4965281-A | CONTROLLING PLANT AND MAMMAL FUNGAL INFECTIONS | E. I. DU PONT DE NEMOURS AND CMOPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4965280-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0390850-A1 | ANTIFUNGAL CARBINOLS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1990-10-10 | — | — | EP | disclosed |
| US-4952232-A | Antifungal carbinols | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-28 | — | — | US | disclosed |
| WO-1989005581-A1 | ANTIFUNGAL CARBINOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-06-29 | — | — | WO | disclosed |
| EP-0251086-A2 | Antifungal carbinols | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |