Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL917203 | 1.00 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CGPIK3CBPDE4D | |
| SCHEMBL917405 | 0.95 | PDE4D (0.43) | PIK3CDPIK3CAPIK3CGPIK3CBPDE4D | |
| SCHEMBL918339 | 0.95 | PDE4D (0.41) | PIK3CDPIK3CAPIK3CGPIK3CBPDE4D | |
| SCHEMBL916681 | 0.91 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CGPIK3CBPDE4D | |
| SCHEMBL918060 | 0.91 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPDE4DPDE4A | |
| SCHEMBL3676661 | 0.91 | PDE4D (0.37) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL3680467 | 0.91 | PDE4D (0.37) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL917973 | 0.88 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL916207 | 0.88 | PDE4D (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBPDE4D | |
| SCHEMBL917070 | 0.88 | PDE4D (0.48) | PIK3CDPIK3CAPIK3CGPIK3CBPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035315-A9 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LAB LTD (IN) | 2008-10-23 | — | — | WO | disclosed |