Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 10/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488576 | 0.96 | GLA (0.57) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL13672254 | 0.95 | GLA (0.56) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL4974209 | 0.94 | GLA (0.61) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL13672250 | 0.93 | GLA (0.58) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL4483444 | 0.92 | GLA (0.63) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL4977107 | 0.92 | GLA (0.61) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL13672247 | 0.91 | GLA (0.60) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL4479905 | 0.90 | GLA (0.59) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL13672249 | 0.90 | GLA (0.59) | GLAALDH1A1MAPTEGFRERBB2 | |
| SCHEMBL4978289 | 0.90 | GLA (0.59) | GLAALDH1A1MAPTEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685114-B1 | ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. | EMS SA (BR) | 2008-10-15 | — | — | EP | claimed |
| EP-1685114-B1 | ANTIBACTERIAL AND/OR ANTIPROTOZOAL NITROIMIDAZOLE DERIVATIVE COMPOUNDS WITH UREASE INHIBITOR ACTIVITY, PROCESS FOR PREPARING THESE COMPOUNDS AND USE IN PHARMACEUTICAL COMPOSITIONS AND MEDICINES. | EMS SA (BR) | 2008-10-15 | — | — | EP | disclosed |