SCHEMBL4975586

SCHEMBL4975586

COc1ccc(Cc2c(C)ccc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2C)cc1

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 17/20 0.65
▸ SLC5A1 P13866 15/20 0.65
▸ ACHE P22303 1/20 0.56
▸ NPC1 O15118 1/20 0.51
▸ RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2574077 0.87 SLC5A2 (0.74) SLC5A2SLC5A1ACHE
SCHEMBL4000120 0.84 SLC5A2 (0.64) SLC5A2SLC5A1ACHENPC1RAB9A
SCHEMBL4000126 0.84 SLC5A2 (0.64) SLC5A2SLC5A1ACHENPC1RAB9A
SCHEMBL28713870 0.82 SLC5A2 (0.74) SLC5A2SLC5A1ACHENPC1RAB9A
SCHEMBL2575031 0.82 SLC5A2 (0.74) SLC5A2SLC5A1ACHENPC1RAB9A
SCHEMBL2577173 0.81 SLC5A2 (0.79) SLC5A2SLC5A1ACHENPC1RAB9A
SCHEMBL2573609 0.80 SLC5A2 (0.74) SLC5A2SLC5A1ACHENPC1RAB9A
SCHEMBL2578940 0.80 SLC5A2 (0.70) SLC5A2SLC5A1ACHENPC1RAB9A
SCHEMBL4359584 0.79 SLC5A2 (0.68) SLC5A2SLC5A1NPC1RAB9A
SCHEMBL4359089 0.79 SLC5A2 (0.68) SLC5A2SLC5A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080045466-A1 Progression Inhibitor For Disease Attributed To Abnormal Accumulation Of Liver Fat KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-02-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045466-A1 Progression Inhibitor For Disease Attributed To Abnormal Accumulation Of Liver Fat SLC10A1, SLC2A2, SLC2A1 SLC5A2 10/4885SLC5A1 12/4885ACHE 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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