Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 9/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.42 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209221 | 0.89 | CCR4 (0.42) | CCR4HTR1AHTR7ALDH1A1MAPT | |
| SCHEMBL4201714 | 0.83 | EPHX2 (0.43) | CCR4ALDH1A1EPHX2 | |
| SCHEMBL4205431 | 0.80 | NPSR1 (0.43) | CCR4ALDH1A1MAPTEPHX2 | |
| SCHEMBL13780306 | 0.76 | NPSR1 (0.43) | CCR4ALDH1A1MAPTTSHR | |
| SCHEMBL4201718 | 0.75 | KDM4E (0.40) | CCR4ALDH1A1EPHX2 | |
| SCHEMBL13780107 | 0.74 | EPHX2 (0.51) | CCR4EPHX2 | |
| SCHEMBL13780154 | 0.74 | EPHX2 (0.52) | CCR4EPHX2 | |
| SCHEMBL13780152 | 0.74 | EPHX2 (0.52) | CCR4EPHX2 | |
| SCHEMBL13780307 | 0.73 | CCR4 (0.44) | CCR4EPHX2 | |
| SCHEMBL4216360 | 0.72 | CCR4 (0.43) | CCR4ALDH1A1MAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1970373-A1 | ALICYCLIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-09-17 | — | — | EP | disclosed |