⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956026 | 1.00 | — | — | |
| SCHEMBL5956305 | 1.00 | — | — | |
| SCHEMBL6225976 | 0.78 | — | — | |
| SCHEMBL19308799 | 0.78 | — | — | |
| SCHEMBL2383860 | 0.72 | — | — | |
| SCHEMBL20201458 | 0.70 | — | — | |
| SCHEMBL12570736 | 0.70 | — | — | |
| SCHEMBL6233396 | 0.70 | KDM4E (0.36) | — | |
| SCHEMBL6234575 | 0.69 | — | — | |
| SCHEMBL5701205 | 0.69 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240299359-A1 | PHARMACEUTICAL COMPOSITION FOR ANIMALS CONTAINING 5-HYDROXY-METHYLIMIDAZOLIDINE-2,4-DIONE COMPOUND AS ACTIVE INGREDIENT | KYONGBO PHARM. CO., LTD. (KR) | 2024-09-12 | — | — | US | claimed |
| EP-3639821-B1 | CARCINOGENESIS INHIBITOR | NAT CANCER CT (JP) | 2024-08-28 | — | — | EP | claimed |
| EP-4364734-A1 | VETERINARY PHARMACEUTICAL COMPOSITION COMPRISING 5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE COMPOUND AS ACTIVE INGREDIENT | Kyongbo Pharm. Co., Ltd. (KR) | 2024-05-08 | — | — | EP | claimed |
| CN-117597121-A | Veterinary drug composition comprising 5-hydroxy-1-methylimidazole-2, 4-dione compound as active ingredient | 京保制药有限公司 | 2024-02-23 | — | — | CN | claimed |
| CN-110740729-B | Carcinogenesis inhibitor | 国立研究开发法人国立癌症研究中心 | 2023-05-16 | — | — | CN | claimed |
| WO-2023277521-A1 | VETERINARY PHARMACEUTICAL COMPOSITION COMPRISING 5-HYDROXY-1-METHYLIMIDAZOLIDINE-2,4-DIONE COMPOUND AS ACTIVE INGREDIENT | 주식회사 경보제약 | 2023-01-05 | — | — | WO | claimed |
| EP-3111934-B1 | PROGRESS-SUPPRESSING OR IMPROVING AGENT FOR CHRONIC KIDNEY DISEASE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2021-09-08 | — | — | EP | claimed |
| CN-111658641-A | Agent for inhibiting or ameliorating the progression of chronic kidney disease | 日本脏器制药株式会社 | 2020-09-15 | — | — | CN | claimed |
| CN-111228259-A | Medical application of 5-hydroxy-1-methylhydantoin | 中国医科大学 | 2020-06-05 | — | — | CN | claimed |
| EP-3072897-B1 | SPIROKETAL DERIVATIVES AND USE THEREOF AS DIABETIC MEDICINE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2019-06-26 | — | — | EP | claimed |
| US-20040063646-A1 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | claimed |
| EP-1400529-A1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE THEREFOR | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-03-24 | — | — | EP | claimed |
| EP-1367060-A1 | GLUCOPYRANOSYLOXYBENZYLBENZENE DERIVATIVES AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-12-03 | — | — | EP | claimed |
| EP-1364958-A1 | GLYCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-11-26 | — | — | EP | claimed |
| EP-1364957-A1 | GLYCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND MEDICINAL USE THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-11-26 | — | — | EP | claimed |
| EP-1354888-A1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-10-22 | — | — | EP | claimed |
| EP-1243261-A1 | Use of a hydantoin derivative in a pharmaceutical composition against hypoalbuminaemia | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2002-09-25 | — | — | EP | claimed |
| EP-0412940-B1 | Hydantoin or imidazolidinetrione derivatives for the prevention or treatment of renal failure | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0412940-A2 | Hydantoin or imidazolidinetrione derivatives for the prevention or treatment of renal failure | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1991-02-13 | — | — | EP | claimed |
| US-4647574-A | Hypoglycemic hydantoin derivatives | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1987-03-03 | — | — | US | claimed |