Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.96 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.96 |
| ▸ | LMNA | P02545 | 5/20 | 0.96 |
| ▸ | MAPT | P10636 | 5/20 | 0.96 |
| ▸ | METAP2 | P50579 | 3/20 | 0.96 |
| ▸ | METAP1 | P53582 | 2/20 | 0.96 |
| ▸ | BRD4 | O60885 | 2/20 | 0.96 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | MPI | P34949 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cloxyquin SCHEMBL29381298 | 0.98 | KDM4E (1.00) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL115838 | 0.98 | KDM4E (1.00) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL4291941 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL4292402 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL4776305 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL4977294 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL360578 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL4978867 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL4302919 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 | |
| Cloxyquin SCHEMBL317736 | 0.96 | KDM4E (0.96) | KDM4EHSP90AA1LMNAMAPTMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112438266-A | Application of 8-hydroxyquinoline manganese, magnesium and nickel complex in preparation of agricultural bactericide | 兰州大学 | 2021-03-05 | — | — | CN | disclosed |
| US-20080063599-A1 | Compounds Which Can Be Used To Diagnose And Monitor Diseases Associated With The Formation Of Amyloid Protein Fibrils | BARNATRON, S.A. (ES) | 2008-03-13 | — | — | US | disclosed |
| EP-1563852-B1 | COMPOUNDS WHICH CAN BE USED TO DIAGNOSE AND MONITOR DISEASES ASSOCIATED WITH THE FORMATION OF AMYLOID PROTEIN FIBRILS | CETIR CT MEDIC S A (ES) | 2007-11-21 | — | — | EP | disclosed |
| EP-1563852-A1 | COMPOUNDS WHICH CAN BE USED TO DIAGNOSE AND MONITOR DISEASES ASSOCIATED WITH THE FORMATION OF AMYLOID PROTEIN FIBRILS | Cetir Centre Medic, S.A. (ES) | 2005-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080063599-A1 | Compounds Which Can Be Used To Diagnose And Monitor Diseases Associated With The Formation Of Amyloid Protein Fibrils | APP, TTR, IAPP | KDM4E 4615/4885HSP90AA1 1019/4885LMNA 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.