SCHEMBL4977962

SCHEMBL4977962

CC(C)(c1cc[c]cc1)c1ccc(O)c(C(C)(C)c2cc[c]cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.50
ALOX15 P16050 4/20 0.46
ALOX12 P18054 2/20 0.46
KLF10 Q13118 1/20 0.44
ESR2 Q92731 5/20 0.43
HSD17B10 Q99714 4/20 0.42
HPGD P15428 3/20 0.42
CYP3A4 P08684 3/20 0.42
TSHR P16473 3/20 0.42
AR P10275 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
HTR6 P50406 1/20 0.42
ESRRG P62508 1/20 0.42
SLC6A3 Q01959 1/20 0.42
RORC P51449 1/20 0.41
ALDH1A1 P00352 6/20 0.38
TDP1 Q9NUW8 3/20 0.38
NR1I2 O75469 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18494 0.83 ESR1 (0.64) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL10719742 0.81 ESR1 (0.59) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL745012 0.81 ESR1 (0.59) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL29547368 0.81 ESR1 (0.59) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL28172693 0.81 ESR1 (0.48) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL6862504 0.80 ESR1 (0.52) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL673990 0.79 ESR1 (0.80) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL9274292 0.79 ESR1 (0.57) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL1176245 0.78 TSHR (0.50) ESR1ALOX15ALOX12KLF10ESR2
SCHEMBL6860459 0.77 ESR1 (0.48) ESR1ALOX15ALOX12KLF10ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1567469-B1 PROCESS FOR PURIFYING BISPHENOL-A DOW GLOBAL TECHNOLOGIES INC (US) 2008-10-29 EP disclosed
US-7067704-B2 Process for purifying bisphenol-a DOW GLOBAL TECHNOLOGIES INC. (US) 2006-06-27 US disclosed
US-20060014986-A1 Process for purifying bisphenol-a BLUE CUBE IP LLC 2006-01-19 US disclosed
EP-1567469-A2 PROCESS FOR PURIFYING BISPHENOL-A DOW GLOBAL TECHNOLOGIES INC. (US) 2005-08-31 EP disclosed
WO-2004048430-A2 PROCESS FOR PURIFYING BISPHENOL-A DOW GLOBAL TECHNOLOGIES INC. (US) 2004-06-10 WO disclosed
EP-0675097-B1 Process for purifying a bisphenol DOW DEUTSCHLAND INC (DE) 1998-04-22 EP disclosed
US-5512700-A Process for purifying a bisphenol DOW DEUTSCHLAND INC. (DE) 1996-04-30 US disclosed
EP-0675097-A1 Process for purifying a bisphenol DOW DEUTSCHLAND INC. (DE) 1995-10-04 EP disclosed
US-4740634-A Process for crystallizing bisphenol-A GENERAL ELECTRIC COMPANY (US) 1988-04-26 US disclosed