Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4978300 | 1.00 | OPRL1 (0.50) | OPRL1AVPR1AMCHR1OPRM1OPRD1 | |
| SCHEMBL4979451 | 0.92 | OPRL1 (0.49) | OPRL1AVPR1AMCHR1 | |
| SCHEMBL4979443 | 0.92 | OPRL1 (0.49) | OPRL1AVPR1AMCHR1 | |
| SCHEMBL4979941 | 0.86 | OPRL1 (0.48) | OPRL1MCHR1OPRM1OPRD1S1PR5 | |
| SCHEMBL14370929 | 0.85 | OPRL1 (0.53) | OPRL1MCHR1OPRM1OPRD1ADRA1A | |
| SCHEMBL4978385 | 0.84 | OPRL1 (0.56) | OPRL1MCHR1OPRM1OPRD1ADRA1A | |
| Trifluoroacetic Acid SCHEMBL4979937 | 0.83 | OPRL1 (0.49) | OPRL1AVPR1AMCHR1OPRM1OPRD1 | |
| Trifluoroacetic Acid SCHEMBL4975845 | 0.82 | OPRL1 (0.53) | OPRL1AVPR1AMCHR1OPRM1OPRD1 | |
| SCHEMBL4980029 | 0.81 | OPRL1 (0.53) | OPRL1MCHR1ADRA1A | |
| SCHEMBL5796200 | 0.80 | OPRL1 (0.51) | OPRL1MCHR1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354925-B2 | Alpha aryl or heteroaryl methyl beta piperidino propanamide compounds as ORL1-receptor antagonists | PFIZER INC. (US) | 2008-04-08 | — | — | US | disclosed |