SCHEMBL4978423

SCHEMBL4978423

C=C(CCCCN)C(=O)N(CCC)CCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.39
CYP2D6 P10635 1/20 0.38
NFKB1 P19838 1/20 0.38
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
BLM P54132 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PLG P00747 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 1/20 0.36
SLC6A2 P23975 1/20 0.36
RECQL P46063 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4978063 0.95 CYP1A2 (0.37) PAOXCYP2D6NFKB1ALDH1A1KMT2A
SCHEMBL4977307 0.91 CA12 (0.40) PAOXCYP2D6NFKB1ALDH1A1MEN1
SCHEMBL6575286 0.90 CA12 (0.35) ALDH1A1CA12CA2CA9HPGD
SCHEMBL4975719 0.87 CA12 (0.39) ALDH1A1MEN1KMT2ANPSR1SLC6A2
SCHEMBL6756914 0.86 CA12 (0.39) ALDH1A1MEN1KMT2AALOX15CA12
SCHEMBL6447601 0.86 CA12 (0.41) PAOXALDH1A1MEN1KMT2ABLM
SCHEMBL2505688 0.85 BLM (0.43) PAOXCYP2D6NFKB1ALDH1A1MEN1
SCHEMBL1629289 0.85 CES1 (0.41) ALDH1A1CA12CA2CA9HPGD
SCHEMBL9150179 0.84 CA1 (0.40) ALDH1A1CA12CA2CA9CYP1A2
SCHEMBL10587439 0.84 CA12 (0.36) ALDH1A1CA12CA2CA9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2818505-B1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2017-02-01 EP disclosed
EP-2787033-B1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
US-9340663-B2 Rubber composition for tire, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-05-17 US disclosed
EP-2818505-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2014-12-31 EP disclosed
US-20140371372-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-12-18 US disclosed
US-20140323660-A1 RUBBER COMPOSITION FOR TIRE, AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-30 US disclosed
US-8865836-B2 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-10-21 US disclosed
EP-2787033-A1 RUBBER COMPOSITION FOR TYRE, AND PNEUMATIC TYRE Sumitomo Rubber Industries, Ltd. (JP) 2014-10-08 EP disclosed
EP-2543702-B1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER IND (JP) 2013-09-11 EP disclosed
US-20130012660-A1 TIRE RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-10 US disclosed
EP-2543702-A1 Tire rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES LIMITED (JP) 2013-01-09 EP disclosed
US-7339005-B2 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-04 US disclosed
US-20040152845-A1 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-08-05 US disclosed
US-4954343-A DRUG DELIVERY, (METH)ACRYLAMIDE WITH AMINO GROUP AS COPOLYMER NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-09-04 US disclosed