Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754832 | 0.89 | NR3C2 (0.60) | NR3C2ELANECTSGPRTN3BRD4 | |
| SCHEMBL755470 | 0.82 | NR3C2 (0.57) | NR3C2KMT2AELANECTSGPRTN3 | |
| SCHEMBL753806 | 0.80 | NR3C2 (0.79) | NR3C2BRD4 | |
| SCHEMBL754798 | 0.75 | NR3C2 (0.74) | NR3C2KMT2ABRD4 | |
| SCHEMBL755722 | 0.75 | NR3C2 (0.56) | NR3C2BRD4 | |
| SCHEMBL755851 | 0.75 | NR3C2 (0.71) | NR3C2KMT2ABRD4 | |
| SCHEMBL755031 | 0.74 | NR3C2 (0.81) | NR3C2KMT2AELANEPRTN3BRD4 | |
| SCHEMBL754185 | 0.73 | NR3C2 (0.61) | NR3C2KMT2A | |
| SCHEMBL753857 | 0.73 | NR3C2 (0.79) | NR3C2BRD4 | |
| SCHEMBL754306 | 0.73 | NR3C2 (0.79) | NR3C2ELANEBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984345-A1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-10-29 | — | — | EP | claimed |
| WO-2007089034-A1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | claimed |