SCHEMBL497899

SCHEMBL497899

CC(=O)OC(CC(F)(F)F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.35
ALOX15 P16050 1/20 0.34
CETP P11597 1/20 0.34
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
KCNH2 Q12809 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
GALR3 O60755 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11550466 0.78 TSHR (0.37) TSHRTDP1ALOX15CETPCHRM2
SCHEMBL18116510 0.77 TSHR (0.36) TSHRTDP1CETPCHRM2CHRM4
SCHEMBL7527175 0.77 TSHR (0.41) TSHRTDP1CETPCHRM2CHRM4
SCHEMBL20412554 0.77 TDP1 (0.38) TSHRTDP1CETPCHRM2CHRM4
SCHEMBL14716866 0.76 TSHR (0.39) TSHRTDP1ALOX15CHRM2CHRM4
SCHEMBL26454936 0.76 TSHR (0.48) TSHRTDP1ALOX15CHRM2CHRM4
SCHEMBL7523865 0.75 TSHR (0.39) TSHRTDP1CETPCHRM2CHRM4
SCHEMBL19395982 0.75 TSHR (0.34) TSHRTDP1CETPCHRM2CHRM4
SCHEMBL7526153 0.75 TSHR (0.39) TSHRTDP1CETPCHRM2CHRM4
SCHEMBL1240025 0.74 TSHR (0.37) TSHRTDP1ALOX15CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150221987-A1 ELECTROLYTIC SOLUTION FOR NON-AQUEOUS SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed
US-20150221987-A1 ELECTROLYTIC SOLUTION FOR NON-AQUEOUS SECONDARY BATTERY, AND NON-AQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-08-06 US disclosed
US-8106222-B2 Fluorine-containing ether compound FUJIFILM CORPORATION (JP) 2012-01-31 US disclosed
US-20090018350-A1 NOVEL FLUORINE-CONTAINING ETHER COMPOUND FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018350-A1 NOVEL FLUORINE-CONTAINING ETHER COMPOUND AFF4, AFF1, AFF2 TSHR 530/4885TDP1 2372/4885ALOX15 3203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.