Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384479 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL294759 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL4575538 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL15873757 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL8811887 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL2431181 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL1410664 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL15326957 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL15326983 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 | |
| SCHEMBL15326981 | 1.00 | ACE2 (0.35) | ACE2LMNAGPR84SPHK1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335725-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | claimed |
| EP-0460882-B1 | Lipopeptide deacylase | LILLY CO ELI (US) | 1996-07-24 | — | — | EP | claimed |
| EP-0460882-A2 | Lipopeptide deacylase | ELI LILLY AND COMPANY (US) | 1991-12-11 | — | — | EP | claimed |
| EP-0010421-B1 | MIXTURE OF ANTIBIOTICS DESIGNATED BY A-21978, PROCESS FOR ITS PRODUCTION, THEIR PHARMACEUTICAL COMPOSITIONS AND PRODUCING MICROORGANISM | ELI LILLY AND COMPANY (US) | 1990-10-10 | — | — | EP | claimed |
| US-RE32455-E | A-21978 antibiotics and process for their production | ELI LILLY AND COMPANY (US) | 1987-07-07 | — | — | US | claimed |
| US-RE32333-E | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1987-01-20 | — | — | US | claimed |
| EP-0095295-B1 | CYCLIC PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-01-14 | — | — | EP | claimed |
| US-RE32311-E | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1986-12-16 | — | — | US | claimed |
| US-4537717-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | claimed |
| US-4482487-A | A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1984-11-13 | — | — | US | claimed |
| EP-0095295-A1 | Cyclic peptide derivatives | ELI LILLY AND COMPANY (US) | 1983-11-30 | — | — | EP | claimed |
| US-RE31396-E | A-21978 Antibiotics and process for their production | ELI LILLY AND COMPANY (US) | 1983-09-27 | — | — | US | claimed |
| US-4396543-A | Derivatives of A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | claimed |
| US-4331594-A | PEPTIDE ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-05-25 | — | — | US | claimed |
| US-4208403-A | A-21978 Antibiotics and process for their production | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | claimed |
| EP-0010421-A1 | Mixture of antibiotics designated by A-21978, process for its production, their pharmaceutical compositions and producing microorganism | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | claimed |
| CN-111358713-B | copolymer | 宝丽化学工业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-111481469-B | copolymer | 宝丽化学工业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| US-4396543-A | Derivatives of A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | disclosed |
| US-4396543-A | Derivatives of A-21978C cyclic peptides | ELI LILLY AND COMPANY (US) | 1983-08-02 | — | — | US | disclosed |