Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4980561 | 1.00 | TSHR (0.44) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL28179534 | 0.89 | TSHR (0.39) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL10512099 | 0.86 | TDP1 (0.36) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL17541867 | 0.82 | TDP1 (0.34) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL1287881 | 0.78 | — | — | |
| SCHEMBL7212827 | 0.78 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL10772647 | 0.74 | TSHR (0.69) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL18187333 | 0.74 | TSHR (0.69) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL18187342 | 0.74 | TSHR (0.69) | TSHRALDH1A1TDP1USP2HPGD | |
| SCHEMBL2846645 | 0.74 | TSHR (0.69) | TSHRALDH1A1TDP1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505945-B1 | SUBSTITUTED CYCLOALKYL P1' HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-11-05 | — | — | EP | disclosed |