⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2174728 | 0.85 | — | — | |
| SCHEMBL2174724 | 0.85 | — | — | |
| SCHEMBL29012324 | 0.79 | CHRM2 (0.30) | — | |
| SCHEMBL29012326 | 0.79 | CHRM2 (0.30) | — | |
| SCHEMBL29864586 | 0.78 | — | — | |
| SCHEMBL4748144 | 0.76 | TP53 (0.32) | — | |
| SCHEMBL1445674 | 0.76 | TP53 (0.32) | — | |
| SCHEMBL4748237 | 0.76 | TP53 (0.32) | — | |
| SCHEMBL6517872 | 0.74 | — | — | |
| SCHEMBL3040787 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076736-A1 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | SKY HIGH, LLC (US) | 2008-03-27 | — | — | US | disclosed |
| EP-1024812-B1 | COMPOSITIONS CONTAINING LYSOPHOSPHATIDIC ACIDS WHICH INHIBIT APOPTOSIS AND USES THEREOF | SKY HIGH LLC (US) | 2007-01-24 | — | — | EP | disclosed |
| US-20060063738-A1 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | SKY HIGH, LLC (US) | 2006-03-23 | — | — | US | disclosed |
| US-6949528-B1 | Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof | GODDARD JOHN G | 2005-09-27 | — | — | US | disclosed |
| US-6949529-B2 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | SKY HIGH, LLC (US) | 2005-09-27 | — | — | US | disclosed |
| US-20030149002-A1 | Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof | SKY HIGH, LLC. | 2003-08-07 | — | — | US | disclosed |
| US-6495532-B1 | PRESERVATION AND TREATMENT OF ORGANS FOR TRANSPLANTATION WITH SUCH AS 3-OLEOYL-2-METHYL-1-THIOPHOSPHATE-GLYCERIDE AND A POTENTIATING COPONENT SUCH AS POLYETHYLENE GLYCOL, A PROTEIN OR A LIPID MEMBRANE | SKY HIGH, LLC | 2002-12-17 | — | — | US | disclosed |