⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088192 | 0.90 | — | — | |
| SCHEMBL27572186 | 0.90 | TSHR (0.60) | — | |
| SCHEMBL28772239 | 0.90 | TSHR (0.60) | — | |
| Glutaral SCHEMBL7938260 | 0.86 | HIF1A (0.77) | — | |
| Glutaral SCHEMBL1285455 | 0.82 | HIF1A (1.00) | — | |
| Glutaral SCHEMBL836 | 0.82 | — | — | |
| SCHEMBL83693 | 0.82 | — | — | |
| SCHEMBL356856 | 0.79 | — | — | |
| Glutaral SCHEMBL8000996 | 0.79 | HIF1A (0.77) | — | |
| Glutaral SCHEMBL27566525 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115872962-B | Beraprost sodium intermediate and preparation method thereof | 成都硕德药业有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-115872962-A | Beraprost sodium intermediate and preparation method thereof | 成都硕德药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| EP-3164127-A1 | COMPOSITIONS AND METHODS TO IMPROVE ADOPTIVE CELL THERAPIES | 7 HILLS INTERESTS, LLC (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016182968-A1 | NOVEL SYRINGOLIN ANALOGUES AND METHODS OF MAKING AND USING SAME | BROWN UNIVERSITY (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016003980-A1 | COMPOSITIONS AND METHODS TO IMPROVE ADOPTIVE CELL THERAPIES | 7 HILLS INTERESTS LLC (US) | 2016-01-07 | — | — | WO | disclosed |
| EP-1987015-A2 | BENZOYL-SUBSTITUTED ALANINES | BASF SE (DE) | 2008-11-05 | — | — | EP | disclosed |
| CN-100375738-C | Preparation method of Polyvinyl ether compound | IDEMITSU KOSAN CO (JP) | 2008-03-19 | — | — | CN | disclosed |
| CN-100343215-C | Polyvinyl ether compound and lubricating oil | IDEMITSU KOSAN CO (JP) | 2007-10-17 | — | — | CN | disclosed |
| WO-2007093539-A2 | BENZOYL-SUBSTITUTED ALANINES | BASF SE (DE) | 2007-08-23 | — | — | WO | disclosed |
| CN-1234737-C | Polyvinyl ether compound and lubricating oil | IDEMITSU KOSAN CO (JP) | 2006-01-04 | — | — | CN | disclosed |
| EP-1392657-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-03-10 | — | — | EP | disclosed |
| EP-1392657-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20040038965-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-02-26 | — | — | US | disclosed |
| WO-2003053331-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-03 | — | — | WO | disclosed |
| CN-1081645-C | Polyvinyl ether compound | IDEMITSU KOSAN CO (JP) | 2002-03-27 | — | — | CN | disclosed |
| CN-1314419-A | Polyvinyl ether compound | IDEMITSU KOSAN CO (JP) | 2001-09-26 | — | — | CN | disclosed |
| CN-1233621-A | Polyvinyl ether compound and lubricating oil | IDEMITSU KOSAN CO (JP) | 1999-11-03 | — | — | CN | disclosed |
| CN-1233620-A | Polyvinyl ether compound and lubricating oil | IDEMITSU KOSAN CO (JP) | 1999-11-03 | — | — | CN | disclosed |
| CN-1233622-A | Polyvinyl ether compound and lubricating oil | IDEMITSU KOSAN CO (JP) | 1999-11-03 | — | — | CN | disclosed |
| CN-1080296-A | polyvinyl ether compound and lubricating oil | IDEMITSU KOSAN CO (JP) | 1994-01-05 | — | — | CN | disclosed |