⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15704277 | 1.00 | — | — | |
| SCHEMBL19242666 | 1.00 | — | — | |
| SCHEMBL14386806 | 1.00 | — | — | |
| SCHEMBL1694138 | 1.00 | — | — | |
| SCHEMBL1682644 | 1.00 | — | — | |
| SCHEMBL283805 | 1.00 | — | — | |
| SCHEMBL307893 | 1.00 | — | — | |
| SCHEMBL12912800 | 1.00 | — | — | |
| SCHEMBL4886742 | 1.00 | — | — | |
| SCHEMBL308247 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118901430-A | Method for reducing occurrence of sunlight rose burning disease by using grape rootstock with branches | 广西壮族自治区农业科学院 | 2024-11-08 | — | — | CN | disclosed |
| CN-112106652-B | Method for screening good variety of fragrant lotus flower fragrance | 江苏开放大学（江苏城市职业学院） | 2022-09-20 | — | — | CN | disclosed |
| US-20170267630-A1 | CLASS-AND ISOFORM-SPECIFIC HDAC INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-09-21 | — | — | US | disclosed |
| US-9682990-B2 | Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2017-06-20 | — | — | US | disclosed |
| US-9682990-B2 | Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2017-06-20 | — | — | US | disclosed |
| US-9540317-B2 | Class- and isoform-specific HDAC inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160318946-A1 | ALCOHOL-, DIOL-, AND CARBOHYDRATE-SUBSTITUTED INDENOISOQUINOLINES AS TOPOISOMERASE I INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-03 | — | — | US | disclosed |
| US-20160318946-A1 | ALCOHOL-, DIOL-, AND CARBOHYDRATE-SUBSTITUTED INDENOISOQUINOLINES AS TOPOISOMERASE I INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-03 | — | — | US | disclosed |
| US-9328073-B2 | Alcohol-, diol-, and carbohydrate-substituted indenoisoquinolines as topoisomerase I inhibitors | PURDUE RESEARCH FOUNDATION (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150307444-A1 | CLASS- AND ISOFORM-SPECIFIC HDAC INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150148370-A1 | ALCOHOL-, DIOL-, AND CARBOHYDRATE-SUBSTITUTED INDENOISOQUINOLINES AS TOPOISOMERASE I INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2015-05-28 | — | — | US | disclosed |
| US-8716344-B2 | Class- and isoform-specific HDAC inhibitors and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-05-06 | — | — | US | disclosed |
| US-20140120107-A1 | GENES OF AN OTITIS MEDIA ISOLATE OF NONTYPEABLE HAEMOPHILUS INFLUENZAE | THE BOARD OF REGENTS OF UNIVERSITY OF OKLAHOMA (US) | 2014-05-01 | — | — | US | disclosed |
| WO-2013000970-A1 | BIS TRIDENTATE W3O2 CLUSTERS FOR X-RAY IMAGING | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-03 | — | — | WO | disclosed |
| WO-2012162513-A2 | ALCOHOL-, DIOL-, AND CARBOHYDRATE-SUBSTITUTED INDENOISOQUINOLINES AS TOPOISOMERASE I INHIBITORS | PURDUE RESEARCH FOUNDATION (US) | 2012-11-29 | — | — | WO | disclosed |
| US-7364885-B2 | Process for producing isoprenoid compounds by microorganisms and a method for screening compounds with antibiotic or weeding activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20070269857-A1 | A PROCESS FOR PRODUCING ISOPRENOID COMPOUNDS BY MICROORGANISMS AND A METHOD FOR SCREENING COMPOUNDS WITH ANTIBIOTIC OR WEEDING ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |