Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4980938 | 1.00 | JAK3 (0.74) | JAK3JAK2 | |
| SCHEMBL4980951 | 1.00 | JAK3 (0.74) | JAK3JAK2 | |
| SCHEMBL4988399 | 0.89 | JAK3 (0.68) | JAK3JAK2 | |
| SCHEMBL4988403 | 0.89 | JAK3 (0.68) | JAK3JAK2 | |
| SCHEMBL4981256 | 0.85 | JAK2 (1.00) | JAK3JAK2 | |
| SCHEMBL4980582 | 0.79 | JAK2 (0.77) | JAK3JAK2 | |
| SCHEMBL4980576 | 0.79 | JAK2 (0.77) | JAK3JAK2 | |
| SCHEMBL4978192 | 0.78 | JAK2 (0.78) | JAK3JAK2 | |
| SCHEMBL4978181 | 0.78 | JAK2 (0.78) | JAK3JAK2 | |
| SCHEMBL4977038 | 0.78 | JAK2 (0.78) | JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132502-A1 | PYRAZOLYL-AMINO-SUBSTITUTED PYRIMIDINES AND THEIR USE FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-11-06 | — | — | WO | disclosed |