Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.63 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.63 |
| ▸ | ITGB7 | P26010 | 14/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769314 | 0.89 | ITGB1 (0.60) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2770988 | 0.88 | ITGB1 (0.62) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2773907 | 0.88 | ITGB1 (0.61) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2770133 | 0.86 | ITGB1 (0.59) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2769577 | 0.85 | ITGB1 (0.69) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL2770949 | 0.85 | ITGB1 (0.69) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4981098 | 0.85 | ITGB1 (0.62) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2770124 | 0.85 | ITGB1 (0.64) | ITGB1ITGA4ITGB7 | |
| SCHEMBL2769387 | 0.85 | ITGB1 (0.61) | ITGB1ITGA4ITGB7ITGAV | |
| SCHEMBL4981105 | 0.84 | ITGB1 (0.61) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335663-B2 | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α4 integrins | ELAN PHARMACEUTICALS, INC. (US) | 2008-02-26 | — | — | US | disclosed |