SCHEMBL498193

SCHEMBL498193

Cc1ccc(OC(=O)c2ccccc2)c(OC(=O)c2ccccc2)c1

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.53
MAPT P10636 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
SLC6A3 Q01959 1/20 0.51
MEN1 O00255 2/20 0.51
CYP3A4 P08684 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
ALDH1A1 P00352 1/20 0.51
CA12 O43570 1/20 0.49
CA9 Q16790 1/20 0.49
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9341345 0.92 KMT2A (0.62) KMT2AMAPTSLC6A3MEN1CYP3A4
SCHEMBL13177335 0.90 PDCD1 (0.49) MAPTSMN1; SMN2ESR1ESR2
SCHEMBL10500437 0.88 MRGPRX4 (0.53) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL9421256 0.88 KMT2A (0.52) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL11490636 0.88 MAPT (0.64) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL20005673 0.88 KMT2A (0.58) KMT2AMAPTSMN1; SMN2MEN1CYP3A4
SCHEMBL31321613 0.88 KMT2A (0.58) KMT2AMAPTSMN1; SMN2MEN1CYP3A4
SCHEMBL28663041 0.86 KMT2A (0.52) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL28677915 0.86 KMT2A (0.46) KMT2AMAPTSMN1; SMN2SLC6A3MEN1
SCHEMBL2060065 0.85 KMT2A (0.49) KMT2AMAPTSMN1; SMN2SLC6A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113773423-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2021-12-10 CN claimed
US-9464144-B2 Enhanced procatalyst composition and process W. R. Grace & Co.—Conn. (US) 2016-10-11 US claimed
CN-104860826-A Production of substituted phenylene aromatic diesters DOW GLOBAL TECHNOLOGIES LLC 2015-08-26 CN claimed
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN disclosed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN disclosed
CN-113773423-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2021-12-10 CN disclosed
EP-3074435-B1 PROCATALYST PARTICLES AND POLYMERIZATION PROCESS FOR IMPACT COPOLYMERS GRACE W R & CO (US) 2021-11-10 EP disclosed
US-20200406213-A1 REMOTE PRESSURE SENSING FOR POLYMER REACTOR CONTROL W. R. GRACE & CO.-CONN. 2020-12-31 US disclosed
CN-106977766-B Thermoformed article with high stiffness and good optical properties 格雷斯公司 2020-03-06 CN disclosed
US-20180305479-A1 Procatalyst Particles And Polymerization Process For Impact Copolymers W. R. GRACE & CO.-CONN. (US) 2018-10-25 US disclosed
WO-2010078519-A1 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO disclosed
US-20100168342-A1 Propylene Impact Copolymer and Method W. R. GRACE & CO.-CONN. 2010-07-01 US disclosed
US-20100168342-A1 Propylene Impact Copolymer and Method W. R. GRACE & CO.-CONN. 2010-07-01 US disclosed
US-20100168342-A1 Propylene Impact Copolymer and Method W. R. GRACE & CO.-CONN. 2010-07-01 US disclosed
US-20100168353-A1 Propylene-Based Polymer, Articles, and Process for Producing Same W.R. GRACE & CO.-CONN. 2010-07-01 US disclosed
US-20100168353-A1 Propylene-Based Polymer, Articles, and Process for Producing Same W.R. GRACE & CO.-CONN. 2010-07-01 US disclosed
US-20100168353-A1 Propylene-Based Polymer, Articles, and Process for Producing Same W.R. GRACE & CO.-CONN. 2010-07-01 US disclosed
US-5288871-A Modify balance between rates of bone resorption and formation AMERICAN HOME PRODUCTS CORPORATION (US) 1994-02-22 US disclosed