Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 12/20 | 0.60 |
| ▸ | PTGFR | P43088 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3175315 | 0.90 | MTTP (0.73) | MTTPPPARGNR1H4 | |
| SCHEMBL4987220 | 0.83 | MEN1 (0.58) | MTTPNPC1RAB9AMAPTPPARG | |
| SCHEMBL2842480 | 0.82 | MTTP (0.61) | MTTP | |
| SCHEMBL4987243 | 0.80 | MTTP (0.60) | MTTPNPC1RAB9A | |
| SCHEMBL5666303 | 0.79 | MTTP (0.56) | MTTP | |
| SCHEMBL4982046 | 0.79 | MTTP (0.56) | MTTPNPC1RAB9APPARGMEN1 | |
| SCHEMBL4989155 | 0.79 | MTTP (0.63) | MTTP | |
| SCHEMBL4988542 | 0.78 | MTTP (0.56) | MTTP | |
| SCHEMBL4987813 | 0.78 | MTTP (0.62) | MTTP | |
| SCHEMBL4981759 | 0.78 | MTTP (0.64) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988920-A1 | METHODS FOR TREATING OBESITY BY ADMINISTERING A TRKB ANTAGONIST | Rinat Neuroscience Corp. (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007088479-A1 | METHODS FOR TREATING OBESITY BY ADMINISTERING A TRKB ANTAGONIST | RINAT NEUROSCIENCE CORP. (US) | 2007-08-09 | — | — | WO | disclosed |