Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.55 |
| ▸ | ERN1 | O75460 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246872 | 0.89 | ERN1 (0.45) | DPP4ERN1ALDH1A1KDM4EGAA | |
| SCHEMBL16835586 | 0.80 | DPP4 (0.60) | DPP4ERN1ALDH1A1KDM4EGAA | |
| SCHEMBL14656756 | 0.78 | ERN1 (0.39) | DPP4ERN1ALDH1A1KDM4EGAA | |
| SCHEMBL10551506 | 0.72 | ERN1 (0.45) | DPP4ERN1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL23611278 | 0.72 | DPP4 (0.65) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL2742433 | 0.72 | DPP4 (0.65) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL13707354 | 0.72 | DPP4 (0.65) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL1105086 | 0.72 | DPP4 (0.65) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| Alpha-Terthienyl SCHEMBL147274 | 0.72 | DPP4 (0.65) | DPP4ALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL499333 | 0.72 | DPP4 (0.65) | DPP4ALDH1A1KDM4EGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106038-B2 | Method for reducing or preventing PDT related inflammation | QLT INC. (CA) | 2012-01-31 | — | — | US | disclosed |
| EP-1229937-A2 | USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA | QLT Inc. (CA) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001035996-A2 | USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA | QLT INC. (CA) | 2001-05-25 | — | — | WO | disclosed |
| WO-2001035997-A2 | USE OF LOW-DOSE PDT TO INHIBIT RESTENOSIS | QLT INC. (CA) | 2001-05-25 | — | — | WO | disclosed |