Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 8/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985903 | 0.92 | SCD (0.49) | SCD | |
| SCHEMBL936926 | 0.90 | SCD (0.57) | SCDALDH1A1KDM4E | |
| SCHEMBL936236 | 0.84 | SCD (0.57) | SCD | |
| SCHEMBL936617 | 0.83 | SCD (0.50) | SCDALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL939274 | 0.81 | SCD (0.65) | SCD | |
| SCHEMBL4986244 | 0.79 | SCD (0.67) | SCD | |
| SCHEMBL1376761 | 0.78 | SCD (0.59) | SCD | |
| SCHEMBL1379527 | 0.77 | SCD (0.77) | SCD | |
| SCHEMBL2466037 | 0.74 | SCD (0.56) | SCD | |
| SCHEMBL936658 | 0.73 | SCD (0.75) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335658-B2 | Pyridazine derivatives and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2008-02-26 | — | — | US | claimed |