Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957065 | 1.00 | BDKRB1 (0.89) | BDKRB1CYP3A4 | |
| SCHEMBL13936517 | 0.95 | BDKRB1 (0.98) | BDKRB1 | |
| SCHEMBL13936516 | 0.94 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4957132 | 0.94 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4959308 | 0.94 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL13936521 | 0.94 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4957986 | 0.94 | BDKRB1 (1.00) | BDKRB1CYP3A4 | |
| SCHEMBL4530960 | 0.94 | BDKRB1 (1.00) | BDKRB1CYP3A4 | |
| SCHEMBL4530961 | 0.94 | BDKRB1 (1.00) | BDKRB1CYP3A4 | |
| SCHEMBL4961593 | 0.93 | BDKRB1 (0.89) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393852-B2 | Piperazine derivatives and methods of use | AMGEN INC. (US) | 2008-07-01 | — | — | US | claimed |