⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986949 | 1.00 | — | — | |
| SCHEMBL30084792 | 0.96 | — | — | |
| SCHEMBL30718065 | 0.96 | — | — | |
| SCHEMBL5699943 | 0.96 | — | — | |
| SCHEMBL5699939 | 0.96 | — | — | |
| SCHEMBL6693116 | 0.96 | — | — | |
| SCHEMBL482331 | 0.77 | — | — | |
| Cyclooctene SCHEMBL4198806 | 0.72 | HDAC3 (0.34) | — | |
| SCHEMBL22253106 | 0.70 | — | — | |
| SCHEMBL14802281 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3103148-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS | cynora GmbH (DE) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015118035-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2015-08-13 | — | — | WO | disclosed |
| EP-2903044-A1 | Organic molecules for use in optoelectronic components | cynora GmbH (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-7361771-B2 | Process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide | WARNER-LAMBERT COMPANY (US) | 2008-04-22 | — | — | US | disclosed |
| EP-1353917-B1 | NOVEL PROCESS FOR THE SYNTHESIS OF 5-(4-FLUOROPHENYL)-1-(2-((2R, 4R)-4-HYDROXY -6-OXO-TETRAHYDRO-PYRAN-2-YL)-ETHYL)-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE | WARNER LAMBERT CO (US) | 2007-03-28 | — | — | EP | disclosed |
| US-7183408-B2 | Process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide | WARNER-LAMBERT COMPANY, LLC (US) | 2007-02-27 | — | — | US | disclosed |
| US-20070032664-A1 | Novel process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide | BUTLER DONALD E | 2007-02-08 | — | — | US | disclosed |
| US-20070032662-A1 | Novel process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrole-3-carboxylic acid and phenylamide | BUTLER DONALD E | 2007-02-08 | — | — | US | disclosed |
| EP-1734034-A2 | Carboxylic acid salts of beta-alanine esters or -amides | Warner-Lambert Company LLC (US) | 2006-12-20 | — | — | EP | disclosed |
| EP-1728785-A1 | 7-[(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrol-1-yl]-heptanoic acid ester 3,5-dioxo-acetal | Warner-Lambert Company LLC (US) | 2006-12-06 | — | — | EP | disclosed |
| EP-1724256-A2 | Novel process for the synthesis of 5-(4-fluorphenyl)-1-2(2-((2r,4r)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl)-2-isopropyl-4-phenyl-1h-pyrrole-3-carboxylic acid phenylamide | Warner-Lambert Company LLC (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20050239869-A1 | Novel process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1eta-pyrrole-3-carboxylic acid phenylamide | BUTLER DONALD E | 2005-10-27 | — | — | US | disclosed |
| EP-1353917-A2 | NOVEL PROCESS FOR THE SYNTHESIS OF 5-(4-FLUOROPHENYL)-1-(2-((2R, 4R)-4-HYDROXY -6-OXO-TETRAHYDRO-PYRAN-2-YL)-ETHYL)-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE | WARNER-LAMBERT COMPANY (US) | 2003-10-22 | — | — | EP | disclosed |
| US-20020133026-A1 | NOVEL PROCESS FOR THE SYNTHESIS OF 5-(4-FLUOROPHENYL)-1-[2-((2R,4R)-4-HYDROXY-6-OXO-TETRAHYDRO-PYRAN-2-YL)-ETHYL]-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE | BUTLER DONALD EUGENE (US) | 2002-09-19 | — | — | US | disclosed |
| WO-2002055519-A2 | NOVEL PROCESS FOR THE SYNTHESIS OF 5-(4-FLUOROPHENYL)-1-[2-((2R, 4R)-4-HYDROXY -6-OXO-TETRAHYDRO-PYRAN-2-YL)-ETHYL]-2-ISOPROPYL-4-PHENYL-1H-PYRROLE-3-CARBOXYLIC ACID PHENYLAMIDE | WARNER LAMBERT CO (US) | 2002-07-18 | — | — | WO | disclosed |
| EP-0750601-B1 | PROCESS FACILITATING THE REGENERATION OF A ZEOLITHE-BASED CATALYST IMPLEMENTED IN AN ACYLATION REACTION AND UTILIZATION | RHODIA CHIMIE SA (FR) | 2000-08-23 | — | — | EP | disclosed |