SCHEMBL49883

SCHEMBL49883

O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
CA4 P22748 3/20 0.39
CA14 Q9ULX7 3/20 0.39
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39
CA3 P07451 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CA1 P00915 1/20 0.39
GLA P06280 1/20 0.39
CA9 Q16790 1/20 0.39
BBOX1 O75936 2/20 0.37
EHMT2 Q96KQ7 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
NR1H2 P55055 2/20 0.37
NR1H3 Q13133 2/20 0.37
ALDH1A1 P00352 4/20 0.35
TSHR P16473 2/20 0.33
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8954345 0.97 ESR1 (0.46) ESR1ESR2CA4CA14CA12
SCHEMBL28287944 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL28590369 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
Fluoride SCHEMBL11421433 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL28720396 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL28580119 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL30499381 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL231521 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL9581966 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12
SCHEMBL8078146 0.97 ESR1 (0.40) ESR1ESR2CA4CA14CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5467 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617947-B2 Flame-retardant flexible coating composition, flame-retardant product having flame-retardant flexible coating layer and method for manufacturing the same AXEED INC. (KR) 2026-05-05 US claimed
EP-4662253-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2025-12-17 EP claimed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP claimed
US-12312494-B2 Resin composition, method for producing same, and multi-liquid curable resin composition KANEKA CORPORATION (JP) 2025-05-27 US claimed
CN-120024900-A Nano silicon carbide microsphere and preparation method and application thereof 苏州纳微先进微球材料应用技术研究所有限公司 2025-05-23 CN claimed
CN-119331234-B Reactive flame-retardant polyether polyol with high adhesion and preparation method thereof 山东一诺威新材料有限公司 2025-05-16 CN claimed
CN-120004602-A Sliding plate brick and preparation method thereof 江苏盛耐新材料有限公司 2025-05-16 CN claimed
CN-119978822-A Antistatic silicone rubber composition and preparation method thereof 杭州之江有机硅化工有限公司 2025-05-13 CN claimed
CN-119614114-A Preparation method of flame-retardant cyanate ester resin adhesive 中国航空工业集团公司济南特种结构研究所 2025-03-14 CN claimed
CN-119591156-A Silicon-carbon composite material, preparation method thereof and lithium ion battery 北京索理德新材料科技有限公司 2025-03-11 CN claimed
EP-0070039-A2 Polymerization catalyst and process for polymerizing alpha-olefins PHILLIPS PETROLEUM COMPANY (US) 1983-01-19 EP claimed
EP-0067067-A2 Dry-developing negative resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
EP-0067066-A2 Dry-developing resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
EP-0053956-A1 Ethylene polymerisation catalyst containing an aromatic silicium compound, and process for its preparation Société Chimique des Charbonnages (FR) 1982-06-16 EP claimed
US-4252877-A Battery electrode JOHNSON, MATTHEY & CO., LIMITED (GB) 1981-02-24 US claimed
US-4243552-A MAGNESIUM CHLORIDE OR MANGANESE CHLORIDE AND ADJUVANT PHILLIPS PETROLEUM COMPANY (US) 1981-01-06 US claimed
EP-0012397-A1 Polymerization catalyst and process for polymerizing alpha-olefins PHILLIPS PETROLEUM COMPANY (US) 1980-06-25 EP claimed
US-4190457-A CONTACTING WITH ORGANOSILICON COMPOUND, DRYING, INCREASING PORE VOLUME PHILLIPS PETROLEUM CO. (US) 1980-02-26 US claimed
US-4039666-A ANTICONVULSANT PHENYLSILANES DOW CORNING CORPORATION (US) 1977-08-02 US claimed
US-3994936-A Catalytic rearrangement HOFFMANN-LA ROCHE INC. (US) 1976-11-30 US claimed