Butane

Butane

SCHEMBL4989873

C=C(C)C.CCC.CCCC

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 3/20 0.31
TSHR P16473 2/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL1735040 0.95
Butane SCHEMBL11833863 0.95 TDP1 (0.40) TDP1HSD17B10ALDH1A1TSHRTP53
Propane SCHEMBL7947279 0.91
Propane SCHEMBL9818020 0.86
Isobutane SCHEMBL27668226 0.84 TSHR (0.35) TDP1HSD17B10TSHR
Hydroxyl Radical SCHEMBL28245477 0.80
Hexane SCHEMBL7632619 0.78 TSHR (0.54) HSD17B10ALDH1A1TSHR
Pentane SCHEMBL9570503 0.78
SCHEMBL28160987 0.78
Butane SCHEMBL27637822 0.78 TSHR (0.42) TDP1HSD17B10ALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190307656-A1 FOAM CONTAINING UNIQUE OIL GLOBULES VYNE PHARMACEUTICALS LTD. (F/K/A FOAMIX PHARMACEUTICALS LTD.) 2019-10-10 US disclosed
US-20170231909-A1 FOAM PREPARED FROM NANOEMULSIONS AND USES FOAMIX PHARMACEUTICALS LTD (IL) 2017-08-17 US disclosed
US-9539208-B2 Foam prepared from nanoemulsions and uses FOAMIX PHARMACEUTICALS LTD. (IL) 2017-01-10 US disclosed
US-20140193502-A1 Foam Prepared From Nanoemulsions And Uses FOAMIX LTD. (IL) 2014-07-10 US disclosed
US-20080138296-A1 Alcohol-free; oil in water nanoemulsion comprising nano oil globules; anionic, cationic or nonionic surfactant stabilizer; water; liquefied or compressed gas propellant; homogeneity, aging resistance; breakable foam in pressurized container; improved bubble size; skin disorders; anticarcinogenic agents FOAMIX LTD. (IL) 2008-06-12 US disclosed
WO-2007102052-A2 FOAM CONTAINING UNIQUE OIL GLOBULES FOAMIX LTD. (US) 2007-09-13 WO disclosed
US-20060233721-A1 Foam containing unique oil globules FOAMIX LTD. (IL) 2006-10-19 US disclosed