⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375030 | 0.95 | — | — | |
| SCHEMBL29666334 | 0.90 | — | — | |
| Iodide SCHEMBL6703307 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL4169129 | 0.90 | — | — | |
| Methyl Alcohol SCHEMBL28045618 | 0.86 | — | — | |
| SCHEMBL10396611 | 0.70 | — | — | |
| SCHEMBL2616763 | 0.70 | — | — | |
| SCHEMBL20008725 | 0.70 | — | — | |
| SCHEMBL7126052 | 0.68 | — | — | |
| SCHEMBL290170 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997686-B | Method for producing 2, 3-biphosphinylpyrazine derivative and method for producing phosphine transition metal complex | 日本化学工业株式会社 | 2023-11-03 | — | — | CN | disclosed |
| US-11773120-B2 | Method for producing optically active 2, 3-bisphosphinopyrazine derivative and method for producing optically active phosphine transition metal complex | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| CN-111655708-B | 2, 3-biphosphinopyrazine derivative, process for producing the same, complex compound, catalyst, and process for producing organoboron compound | 日本化学工业株式会社 | 2023-08-25 | — | — | CN | disclosed |
| US-11084835-B2 | 2,3-bisphosphinopyrazine derivative, method for producing same, transition metal complex, asymmetric catalyst, and method for producing organic boron compound | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2021-08-10 | — | — | US | disclosed |
| US-11021500-B2 | Process for preparing optically active 2,3-bisphosphino-substituted quinoxalines | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2021-06-01 | — | — | US | disclosed |
| US-20210047351-A1 | 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2021-02-18 | — | — | US | disclosed |
| US-20200247833-A1 | METHOD FOR PRODUCING 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, AND METHOD FOR PRODUCING PHOSPHINE TRANSITION METAL COMPLEX | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-08-06 | — | — | US | disclosed |
| US-20200087330-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2, 3-BISPHOSPHINOPYRAZINE DERIVATIVE AND METHOD FOR PRODUCING OPTICALLY ACTIVE PHOSPHINE TRANSITION METAL COMPLEX | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-03-19 | — | — | US | disclosed |
| WO-2019172150-A1 | 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND | 日本化学工業株式会社 | 2019-09-12 | — | — | WO | disclosed |
| US-10111892-B2 | Anti-cancer agent | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2018-10-30 | — | — | US | disclosed |
| US-20120252762-A1 | ANTI-CANCER AGENT | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-2502627-A1 | ANTI-CANCER AGENT | Nippon Chemical Industrial Co., Ltd. (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-7414156-B2 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER LAMBERT CO. (US) | 2008-08-19 | — | — | US | disclosed |
| US-20050124830-A1 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | HOGE GARRETT S II (US) | 2005-06-09 | — | — | US | disclosed |
| US-6855849-B2 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER-LAMBERT COMPANY (US) | 2005-02-15 | — | — | US | disclosed |
| US-20040138487-A1 | Bisphospholane ligands with metals for hydrogenation catalysts for enantiomorphs | HOGE GARRETT STEWART | 2004-07-15 | — | — | US | disclosed |
| US-6689915-B2 | AS CATALYSTS FOR USE IN ASYMMETRIC TRANSFORMATION REACTIONS TO PROVIDE HIGH ENANTIOMERIC EXCESSES OF FORMED COMPOUNDS | WARNER-LAMBERT COMPANY LLC | 2004-02-10 | — | — | US | disclosed |
| US-20030073868-A1 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER-LAMBERT COMPANY | 2003-04-17 | — | — | US | disclosed |
| US-20020143214-A1 | Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | HOGE GARRETT STEWART (US) | 2002-10-03 | — | — | US | disclosed |
| EP-1243591-A2 | Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER-LAMBERT COMPANY (US) | 2002-09-25 | — | — | EP | disclosed |