Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 13/20 | 0.43 |
| ▸ | F10 | P00742 | 13/20 | 0.43 |
| ▸ | PLAU | P00749 | 13/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5001225 | 1.00 | F9 (0.43) | F9F10PLAUSLC6A2SLC6A4 | |
| SCHEMBL5025092 | 0.87 | F9 (0.47) | F9F10PLAU | |
| SCHEMBL5025098 | 0.87 | F9 (0.47) | F9F10PLAU | |
| SCHEMBL14091599 | 0.81 | SLC6A2 (0.40) | F9F10PLAUSLC6A2SLC6A4 | |
| SCHEMBL14091617 | 0.81 | SLC6A2 (0.40) | F9F10PLAUSLC6A2SLC6A4 | |
| SCHEMBL14091600 | 0.81 | SLC6A2 (0.40) | F9F10PLAUSLC6A2SLC6A4 | |
| SCHEMBL14091616 | 0.81 | SLC6A2 (0.40) | F9F10PLAUSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5003396 | 0.80 | SLC6A2 (0.40) | F9F10PLAUSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4997560 | 0.80 | SLC6A2 (0.40) | F9F10PLAUSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL4997546 | 0.80 | SLC6A2 (0.40) | F9F10PLAUSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410996-B2 | 3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-7410996-B2 | 3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-7410996-B2 | 3-aryloxy/thio-2,3-substituted propanamines and their use in inhibiting serotonin and norepinephrine reuptake | ELI LILLY AND COMPANY (US) | 2008-08-12 | — | — | US | disclosed |