Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137287 | 1.00 | C3AR1 (0.70) | C3AR1 | |
| SCHEMBL4995868 | 0.90 | C3AR1 (0.66) | C3AR1 | |
| SCHEMBL4996254 | 0.89 | C3AR1 (0.65) | C3AR1 | |
| SCHEMBL4986846 | 0.89 | C3AR1 (0.65) | C3AR1 | |
| SCHEMBL21129414 | 0.87 | C3AR1 (0.55) | C3AR1 | |
| SCHEMBL4992256 | 0.87 | C3AR1 (0.62) | C3AR1 | |
| SCHEMBL4994140 | 0.87 | C3AR1 (0.62) | C3AR1 | |
| SCHEMBL14090816 | 0.86 | C3AR1 (0.67) | C3AR1 | |
| SCHEMBL21129159 | 0.86 | C3AR1 (0.54) | C3AR1 | |
| SCHEMBL16144988 | 0.85 | C3AR1 (0.53) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776411-B1 | MODULATORS OF C3A RECEPTORS | UNIV QUEENSLAND (AU) | 2019-06-26 | — | — | EP | disclosed |
| US-9586914-B2 | Modulators of C3a receptors | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-03-07 | — | — | US | disclosed |
| US-9586914-B2 | Modulators of C3a receptors | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-03-07 | — | — | US | disclosed |
| US-20140302069-A1 | MODULATORS OF C3A RECEPTORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2014-10-09 | — | — | US | disclosed |
| US-20140302069-A1 | MODULATORS OF C3A RECEPTORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2014-10-09 | — | — | US | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | C3AR1 1/4885 |
| US-20140302069-A1 | MODULATORS OF C3A RECEPTORS | C3AR1, C5AR2, C5AR1 | C3AR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.