SCHEMBL499441

SCHEMBL499441

Clc1ccc(Br)cc1Cc1ccc(OCCOC2CC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 18/20 0.57
SLC5A1 P13866 6/20 0.57
CCR5 P51681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31086477 1.00 SLC5A2 (0.57) SLC5A2SLC5A1CCR5
SCHEMBL499621 0.96 SLC5A2 (0.57) SLC5A2SLC5A1CCR5
SCHEMBL499929 0.95 SLC5A2 (0.58) SLC5A2SLC5A1CCR5
SCHEMBL499870 0.94 SLC5A2 (0.57) SLC5A2SLC5A1
SCHEMBL3684929 0.90 SLC5A2 (0.48) SLC5A2SLC5A1CCR5
SCHEMBL499760 0.88 SLC5A2 (0.48) SLC5A2SLC5A1
SCHEMBL499759 0.88 SLC5A2 (0.48) SLC5A2SLC5A1
SCHEMBL3794861 0.88 SLC5A2 (0.48) SLC5A2SLC5A1
SCHEMBL15308120 0.87 SLC5A2 (0.59) SLC5A2SLC5A1
SCHEMBL21942200 0.87 SLC5A2 (0.59) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056984-A1 A NOVEL PROCESS FOR THE PREPARATION OF BEXAGLIFLOZIN A SGLT2 INHIBITOR AND ITS INTERMEDIATES THEREOF VIJAYASRI ORGANICS PRIVATE LIMITED (IN) 2025-03-20 WO disclosed
CN-119219714-A Preparation method of Lijing intermediate compound 浙江永太科技股份有限公司 2024-12-31 CN disclosed
CN-118851889-A Preparation method of Liujing intermediate 浙江永太科技股份有限公司 2024-10-29 CN disclosed
US-10981942-B2 Crystalline form of benzylbenzene SGLT2 inhibitor THERACOS SUB, LLC (US) 2021-04-20 US disclosed
US-10981942-B2 Crystalline form of benzylbenzene SGLT2 inhibitor THERACOS SUB, LLC (US) 2021-04-20 US disclosed
US-20200239510-A1 CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR THERACOSBIO, LLC 2020-07-30 US disclosed
US-20200239510-A1 CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR THERACOSBIO, LLC 2020-07-30 US disclosed
EP-2580225-B1 CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR THERACOS SUB LLC (US) 2018-07-18 EP disclosed
EP-2580225-B1 CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR THERACOS SUB LLC (US) 2018-07-18 EP disclosed
EP-3318562-A2 BENZYLBENZENE DERIVATIVES AND METHODS OF USE Theracos Sub, LLC (US) 2018-05-09 EP disclosed
US-20100222599-A1 PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS THERACOSBIO, LLC 2010-09-02 US disclosed
US-20100222599-A1 PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS THERACOSBIO, LLC 2010-09-02 US disclosed
EP-2187742-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE Theracos, Inc. (US) 2010-05-26 EP disclosed
WO-2010022313-A2 PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS THERACOS, INC. (US) 2010-02-25 WO disclosed
WO-2010022313-A2 PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS THERACOS, INC. (US) 2010-02-25 WO disclosed
US-20090118201-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOSBIO, LLC 2009-05-07 US disclosed
US-20090118201-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOSBIO, LLC 2009-05-07 US disclosed
US-20090118201-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOSBIO, LLC 2009-05-07 US disclosed
WO-2009026537-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2009-02-26 WO disclosed
WO-2009026537-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2009-02-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10981942-B2 Crystalline form of benzylbenzene SGLT2 inhibitor SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885CCR5 1183/4885
US-20090118201-A1 BENZYLBENZENE DERIVATIVES AND METHODS OF USE SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885CCR5 1332/4885
US-20100222599-A1 PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885CCR5 2635/4885
US-20200239510-A1 CRYSTALLINE FORM OF BENZYLBENZENE SGLT2 INHIBITOR SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885CCR5 1183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.