Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.83 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL499703 | 0.98 | TSHR (0.79) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL14995 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL15200 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL7769529 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL22579031 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL1977194 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL6655183 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL11775454 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL21853811 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB | |
| SCHEMBL21853806 | 0.91 | TSHR (1.00) | TSHREPHX1THRBNAAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321110-A | Thickeners for shampoo, hair conditioners | ISP INVESTMENTS INC. (US) | 1994-06-14 | — | — | US | claimed |
| US-3954960-A | Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone | GAF CORPORATION (US) | 1976-05-04 | — | — | US | claimed |
| EP-3347446-B1 | A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE | ISP INVESTMENTS LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| US-12096767-B2 | Residual disinfectant composition | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2024-09-24 | — | — | US | disclosed |
| EP-3328373-B1 | DISINFECTANT COMPOSITION WITH RAPID ANTIVIRAL EFFICACY | KIMBERLY CLARK CO (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3569682-B1 | LIQUID HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY | PROCTER & GAMBLE (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2022162221-A1 | DETERGENT COMPOSITION | UNILEVER IP HOLDINGS B.V. (NL) | 2022-08-04 | — | — | WO | disclosed |
| US-11384316-B2 | Stable laundry cleaning composition and method comprising a polyAPTAC-containing polymer | ISP INVESTMENTS LLC (US) | 2022-07-12 | — | — | US | disclosed |
| US-10995302-B2 | Liquid acidic hard surface cleaning compositions having improved viscosity | THE PROCTER & GAMBLE COMPANY (US) | 2021-05-04 | — | — | US | disclosed |
| US-20210092949-A1 | Residual Disinfectant Composition | KIMBERLY-CLARK WORLDWIDE, INC. | 2021-04-01 | — | — | US | disclosed |
| US-10920180-B2 | Liquid acidic hard surface cleaning compositions providing improved maintenance of surface shine, and prevention of water marks and splash marks | THE PROCTER & GAMBLE COMPANY (US) | 2021-02-16 | — | — | US | disclosed |
| US-20050159321-A1 | Disinfecting compositions containing a polymer complex of an organic acid | RECKITT BENCKISER INC MORRIS CORPORATE CENTER IV (US) | 2005-07-21 | — | — | US | disclosed |
| EP-1531671-A1 | DISINFECTING COMPOSITIONS CONTAINING A POLYMER COMPLEX OF AN ORGANIC ACID | Reckitt Benckiser Inc. (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1442110-A1 | HARD SURFACE CLEANING AND DISINFECTING COMPOSITIONS | Reckitt Benckiser Inc. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2004016087-A1 | DISINFECTING COMPOSITIONS CONTAINING A POLYMER COMPLEX OF AN ORGANIC ACID | RECKITT BENCKISER INC. (US) | 2004-02-26 | — | — | WO | disclosed |
| WO-2003038025-A1 | HARD SURFACE CLEANING AND DISINFECTING COMPOSITIONS | RECKITT BENCKISER INC (US) | 2003-05-08 | — | — | WO | disclosed |
| US-5321110-A | Thickeners for shampoo, hair conditioners | ISP INVESTMENTS INC. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5045617-A | Zwitterion terpolymers of a vinyl lactam, an amino alkyl acrylamide or acrylate, and a polymerizable carboxylic acid | ISP INVESTMENTS INC. (US) | 1991-09-03 | — | — | US | disclosed |
| US-3980769-A | ANIONIC AND AMPHOTERIC SURFACTANTS | L'OREAL (FR) | 1976-09-14 | — | — | US | disclosed |
| US-3954960-A | Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone | GAF CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210092949-A1 | Residual Disinfectant Composition | QARS1, EIF2AK2, POLL | TSHR 2755/4885EPHX1 3996/4885THRB 4598/4885 |
| US-12096767-B2 | Residual disinfectant composition | QARS1, EIF2AK2, POLL | TSHR 2755/4885EPHX1 3996/4885THRB 4598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.