Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994964 | 0.86 | CDC7 (0.51) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL14188533 | 0.85 | CDC7 (0.54) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL4996453 | 0.84 | CDC7 (0.51) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL5000322 | 0.84 | CDC7 (0.51) | CDC7PIM1PIM2NISCHMAPKAPK2 | |
| SCHEMBL5002623 | 0.84 | CDC7 (0.51) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL4995841 | 0.82 | CDC7 (0.54) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL4991296 | 0.82 | CDC7 (0.54) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL4993179 | 0.81 | CDC7 (0.53) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL14188697 | 0.81 | CDC7 (0.48) | CDC7PIM1PIM2MAPKAPK2 | |
| SCHEMBL14188471 | 0.81 | CDC7 (0.52) | CDC7PIM1PIM2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | HANAU CATHLEEN E | 2008-05-15 | — | — | US | disclosed |
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | HANAU CATHLEEN E | 2008-05-15 | — | — | US | disclosed |
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | HANAU CATHLEEN E | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | MKNK2, MAPKAPK2, MAP3K2 | CDC7 487/4885PIM1 539/4885PIM2 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.