⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12496179 | 0.94 | — | — | |
| SCHEMBL169073 | 0.87 | — | — | |
| SCHEMBL19637957 | 0.84 | — | — | |
| SCHEMBL3655504 | 0.84 | — | — | |
| SCHEMBL30888737 | 0.79 | TTR (0.35) | — | |
| SCHEMBL628132 | 0.77 | — | — | |
| Magnesium SCHEMBL31150762 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL18282347 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL3457354 | 0.73 | TSHR (0.33) | — | |
| SCHEMBL6923843 | 0.73 | MEN1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329312-B | Tetracycline compounds | 四相制药公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-108329312-A | Tetracycline compounds | 四相制药公司 | 2018-07-27 | — | — | CN | disclosed |
| CN-108276404-A | Tetracycline compounds | 四相制药公司 | 2018-07-13 | — | — | CN | disclosed |
| CN-104768922-B | Tetracycline compounds | 四相制药公司 | 2018-04-03 | — | — | CN | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| US-20060229280-A1 | Endothelin antagonists | ABBVIE INC. | 2006-10-12 | — | — | US | disclosed |
| EP-0885215-B1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | ABBOTT LAB (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1609790-A2 | Benzo-1,3-dioxolyl- and benzofuranyl substituted pyrrolidine derivatives as endothelin antagonists | Abbott Laboratories (US) | 2005-12-28 | — | — | EP | disclosed |
| US-6946481-B1 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2005-09-20 | — | — | US | disclosed |
| EP-0885215-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | Abbott Laboratories (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997030045-A1 | NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS | ABBOTT LABORATORIES (US) | 1997-08-21 | — | — | WO | disclosed |
| US-4707182-A | Phenoxine-ketal ethers, compositions containing them and the use thereof | CIBA-GEIGY CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| US-4576628-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1986-03-18 | — | — | US | disclosed |
| US-4532732-A | PLANT SAFENING AGENTS AND CHLOROACETANILIDE HERBICIDES FOR SERGHUM, RICE AND BARLEY | CIBA-GEIGY CORPORATION (US) | 1985-08-06 | — | — | US | disclosed |
| US-4530716-A | Plant safening agent | CIBA-GEIGY CORPORATION (US) | 1985-07-23 | — | — | US | disclosed |
| EP-0089313-B1 | OXIME ETHERS, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THE OXIME ETHERS AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-05-02 | — | — | EP | disclosed |
| US-4497648-A | ANTIDOTES FOR HERBICIDES FOR PLANTS | CIBA-GEIGY CORPORATION (US) | 1985-02-05 | — | — | US | disclosed |
| EP-0089313-A1 | Oxime ethers, process for their preparation, compositions containing the oxime ethers and their use | CIBA-GEIGY AG (CH) | 1983-09-21 | — | — | EP | disclosed |
| US-4097491-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |