SCHEMBL4996575

SCHEMBL4996575

CS(=O)(=O)c1ccc2cc(S3(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)CCCC3)ccc2c1

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.34
CA2 P00918 8/20 0.34
JAK2 O60674 1/20 0.34
JAK3 P52333 1/20 0.34
PTK2 Q05397 1/20 0.34
PTGS1 P23219 6/20 0.31
AKR1C3 P42330 2/20 0.31
AKR1C2 P52895 2/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
PTGS2 P35354 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4994087 0.89 CA1 (0.35) CA1CA2
SCHEMBL5002024 0.86 CA1 (0.33) CA1CA2
SCHEMBL4997241 0.86 CA1 (0.34) CA1CA2
SCHEMBL5002059 0.85 KMT2A (0.38) CA1CA2MEN1KMT2APTGS2
SCHEMBL4996370 0.85 CA1 (0.32) CA1CA2
SCHEMBL4992954 0.85 CA1 (0.35) CA1CA2
SCHEMBL5002043 0.84 CA1 (0.32) CA1CA2
SCHEMBL5002205 0.84 CA1 (0.31) CA1CA2
SCHEMBL4993977 0.84 CA1 (0.32) CA1CA2
SCHEMBL4994457 0.83 CA1 (0.31) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371503-B2 Sulfonium salt compound, photoacid generator, and positive-tone radiation-sensitive resin composition JSR CORPORATION (JP) 2008-05-13 US disclosed
US-20060141383-A1 Sulfonium salts, radiation- sensitive acid generators, and positive radiator-sensitive resin compositions JSR CORPORATION (JP) 2006-06-29 US disclosed
EP-1586570-A1 SULFONIUM SALTS, RADIATION-SENSITIVE ACID GENERATORS, AND POSITIVE RADIATION-SENSITIVE RESIN COMPOSITIONS JSR Corporation (JP) 2005-10-19 EP disclosed