SCHEMBL499986

SCHEMBL499986

CCCCCCCCC=COC(=O)CCC(=O)OC=CCCCCCCCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.53
PPARD Q03181 5/20 0.53
PPARA Q07869 5/20 0.53
F7 P08709 4/20 0.53
F3 P13726 4/20 0.53
TERT O14746 3/20 0.53
PTPN1 P18031 3/20 0.53
HSD17B10 Q99714 3/20 0.53
FABP4 P15090 3/20 0.53
CYP1A2 P05177 2/20 0.53
MAPT P10636 2/20 0.53
CYP2C19 P33261 2/20 0.53
BLM P54132 2/20 0.53
FAAH O00519 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 2/20 0.53
ALOX15 P16050 2/20 0.53
DUSP3 P51452 2/20 0.53
CYP19A1 P11511 2/20 0.53
PTGS1 P23219 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL593337 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL258564 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL6255727 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL544208 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL41307 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL1317133 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL3883983 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL3883975 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL4638672 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3
SCHEMBL7571463 1.00 PPARG (0.53) PPARGPPARDPPARAF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8105743-B2 Having hemispherical polysiloxane crosslinked structure; prevents movement from surface functional sites; adhesion RICOH COMPANY, LTD. (JP) 2012-01-31 US disclosed
US-7803508-B2 Toner as well as developer and image forming method using the same RICOH COMPANY, LTD. (JP) 2010-09-28 US disclosed
US-20080226998-A1 FINE ORGANIC SILICONE PARTICLE FOR LATENT ELECTROSTATIC IMAGE DEVELOPING TONERS, EXTERNAL ADDITIVE FOR TONERS, TONER FOR DEVELOPING LATENT ELECTROSTATIC IMAGE, AND TWO-COMPONENT DEVELOPER RICOH COMPANY, LTD. (JP) 2008-09-18 US disclosed
US-20070218387-A1 TONER AS WELL AS DEVELOPER AND IMAGE FORMING METHOD USING THE SAME RICOH COMPANY, LTD. (JP) 2007-09-20 US disclosed