Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.60 |
| ▸ | TACR3 | P29371 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536795 | 0.84 | DHODH (0.42) | DHODHPDE10ALMNATSHRCYP2D6 | |
| Oxycinchophen SCHEMBL31654029 | 0.76 | DHODH (1.00) | DHODHPDE10ATACR3LMNATSHR | |
| Oxycinchophen SCHEMBL1170683 | 0.76 | DHODH (1.00) | DHODHPDE10ATACR3LMNATSHR | |
| Oxycinchophen SCHEMBL29460357 | 0.76 | DHODH (1.00) | DHODHPDE10ATACR3LMNATSHR | |
| SCHEMBL19328453 | 0.75 | DHODH (0.62) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL19328541 | 0.75 | PTGFR (0.56) | CYP3A4 | |
| SCHEMBL19328543 | 0.75 | PTGFR (0.51) | DHODHMAPT | |
| SCHEMBL9501979 | 0.74 | DHODH (1.00) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL13971502 | 0.74 | DHODH (0.77) | DHODHPDE10ATACR3LMNATSHR | |
| SCHEMBL4601632 | 0.74 | DHODH (0.77) | DHODHPDE10ATACR3LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194623-A1 | Method for the Synthesis of Quinoline Derivatives | LABAW CLIFFORD S | 2008-08-14 | — | — | US | claimed |
| EP-1919871-A2 | METHOD FOR THE SYNTHESIS OF QUINOLI E DERIVATIVES | Smithkline Beecham Corporation (US) | 2008-05-14 | — | — | EP | claimed |
| WO-2007016609-A2 | METHOD FOR THE SYNTHESIS OF QUINOLIΝE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-08 | — | — | WO | claimed |
| US-20080194623-A1 | Method for the Synthesis of Quinoline Derivatives | LABAW CLIFFORD S | 2008-08-14 | — | — | US | disclosed |
| EP-1919871-A2 | METHOD FOR THE SYNTHESIS OF QUINOLI E DERIVATIVES | Smithkline Beecham Corporation (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007016609-A2 | METHOD FOR THE SYNTHESIS OF QUINOLIΝE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194623-A1 | Method for the Synthesis of Quinoline Derivatives | NQO2, CYP3A4, NQO1 | DHODH 262/4885PDE10A 1790/4885TACR3 1554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.