Dimethylamine

Dimethylamine

SCHEMBL500187

C=C(C)C(=O)OCCCCC.CNC

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.85
EPHX1 P07099 1/20 0.53
THRB P10828 1/20 0.53
NAAA Q02083 1/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
FAAH O00519 1/20 0.43
ACHE P22303 6/20 0.43
HCAR2 Q8TDS4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL8101078 0.98 TSHR (0.89) TSHREPHX1THRBNAAAALDH1A1
Dimethylamine SCHEMBL28018808 0.94 TSHR (0.75) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL36680 0.94 TSHR (0.96) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL14995 0.92 TSHR (1.00) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL22579031 0.92 TSHR (1.00) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL25293880 0.92 TSHR (1.00) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL21853811 0.92 TSHR (1.00) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL21853806 0.92 TSHR (1.00) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL11775454 0.92 TSHR (1.00) TSHREPHX1THRBNAAAALDH1A1
SCHEMBL1977194 0.92 TSHR (1.00) TSHREPHX1THRBNAAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US claimed
EP-0106193-A2 Liquid skin cleanser composition UNION CARBIDE CORPORATION (US) 1984-04-25 EP claimed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US claimed
US-12096767-B2 Residual disinfectant composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-09-24 US disclosed
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy KIMBERLY-CLARK WORLDWIDE, INC. 2023-09-07 US disclosed
EP-3328373-B1 DISINFECTANT COMPOSITION WITH RAPID ANTIVIRAL EFFICACY KIMBERLY CLARK CO (US) 2023-06-07 EP disclosed
EP-3569682-B1 LIQUID HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY PROCTER & GAMBLE (US) 2022-12-07 EP disclosed
WO-2022162221-A1 DETERGENT COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2022-08-04 WO disclosed
US-10995302-B2 Liquid acidic hard surface cleaning compositions having improved viscosity THE PROCTER & GAMBLE COMPANY (US) 2021-05-04 US disclosed
US-20210092949-A1 Residual Disinfectant Composition KIMBERLY-CLARK WORLDWIDE, INC. 2021-04-01 US disclosed
US-10920180-B2 Liquid acidic hard surface cleaning compositions providing improved maintenance of surface shine, and prevention of water marks and splash marks THE PROCTER & GAMBLE COMPANY (US) 2021-02-16 US disclosed
US-6063368-A MIXTURE OF FOAMING AGENT, WATER SOLUBLE FILM FORMING QUATERNIZED POLYMER AND WATER AVEDA CORPORATION (US) 2000-05-16 US disclosed
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US disclosed
US-5045617-A Zwitterion terpolymers of a vinyl lactam, an amino alkyl acrylamide or acrylate, and a polymerizable carboxylic acid ISP INVESTMENTS INC. (US) 1991-09-03 US disclosed
US-4465802-A WITH WATER SOLUBLE CATIONIC POLYMER AND CATIONIC SURFACTANT UNION CARBIDE CORPORATION (US) 1984-08-14 US disclosed
US-4362528-A OXIDATION COLOR DYE,CATIONIC POLYMER TO IMPROVE FEEL,SHAMPOO WITH ANIONIC DETERGENT SOCIETE ANONYME DITE: L'OREAL (FR) 1982-12-07 US disclosed
US-4314807-A CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO L'OREAL (FR) 1982-02-09 US disclosed
US-3980769-A ANIONIC AND AMPHOTERIC SURFACTANTS L'OREAL (FR) 1976-09-14 US disclosed
US-3958581-A Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair L'OREAL (FR) 1976-05-25 US disclosed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210092949-A1 Residual Disinfectant Composition QARS1, EIF2AK2, POLL TSHR 2755/4885EPHX1 3996/4885THRB 4598/4885
US-12096767-B2 Residual disinfectant composition QARS1, EIF2AK2, POLL TSHR 2755/4885EPHX1 3996/4885THRB 4598/4885
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy EIF2AK2, APOBEC3A, APOBEC3C TSHR 2150/4885EPHX1 1139/4885THRB 4223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.