⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811073 | 1.00 | — | — | |
| SCHEMBL906829 | 0.67 | — | — | |
| SCHEMBL312784 | 0.55 | — | — | |
| SCHEMBL6238732 | 0.55 | — | — | |
| SCHEMBL500342 | 0.54 | — | — | |
| SCHEMBL14452825 | 0.53 | — | — | |
| SCHEMBL14026153 | 0.53 | — | — | |
| SCHEMBL269336 | 0.53 | — | — | |
| SCHEMBL13270768 | 0.50 | — | — | |
| SCHEMBL22689369 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174540-A1 | 3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | GRUENENTHAL GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| US-11572374-B2 | N-cyano-7-azanorbornane derivatives and uses thereof | AMGEN INC. (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210179627-A1 | 3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | Grünenthal GmbH (DE) | 2021-06-17 | — | — | US | disclosed |
| US-20200399280-A1 | 3-(Carboxymethyl)-8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | Grünenthal GmbH (DE) | 2020-12-24 | — | — | US | disclosed |
| US-10807989-B2 | 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives | Grünenthal GmbH (DE) | 2020-10-20 | — | — | US | disclosed |
| US-20190106430-A1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2019-04-11 | — | — | US | disclosed |
| US-20180282341-A1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2018-10-04 | — | — | US | disclosed |
| US-9756858-B2 | Insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-12 | — | — | US | disclosed |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| US-9403845-B2 | Pesticidally active pyridyl- and pyrimidyl- substituted pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| WO-2006111341-A1 | CYANO ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-10-26 | — | — | WO | disclosed |
| US-20060135517-A1 | Imidazolopyridines and methods of making and using the same | BIOGEN IDEC MA INC. | 2006-06-22 | — | — | US | disclosed |
| WO-2006040113-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-20 | — | — | WO | disclosed |
| WO-2006032462-A1 | NOVEL INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-03-30 | — | — | WO | disclosed |
| US-20060052247-A1 | Novel herbicides | SYNGENTA CROP PROTECTION, INC. | 2006-03-09 | — | — | US | disclosed |
| WO-2006024523-A1 | PHTHALAMIDE DERIVATIVES FOR USE AS INSECTICIDES | SYNGENTA PARTICIPATION AG (CH) | 2006-03-09 | — | — | WO | disclosed |
| CN-1732166-A | Novel herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2006-02-08 | — | — | CN | disclosed |
| US-20050222197-A1 | Novel pyrazolopyridine derivatives as pharmaceutical agents | BEIGHT DOUGLAS W | 2005-10-06 | — | — | US | disclosed |
| EP-1578747-A2 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058712-A2 | HERBICIDALLY ACTIVE NICOTINOYL DERIVATES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-07-15 | — | — | WO | disclosed |