Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.79 |
| ▸ | CCR3 | P51677 | 20/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180036 | 0.96 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL180038 | 0.96 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL5048466 | 0.92 | HRH1 (0.79) | HRH1CCR3KCNH2 | |
| SCHEMBL5048469 | 0.92 | HRH1 (0.79) | HRH1CCR3KCNH2 | |
| SCHEMBL180185 | 0.90 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL180014 | 0.88 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL180183 | 0.88 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180119 | 0.88 | HRH1 (1.00) | HRH1CCR3KCNH2 | |
| SCHEMBL180015 | 0.88 | HRH1 (0.85) | HRH1CCR3KCNH2 | |
| SCHEMBL180263 | 0.87 | HRH1 (0.98) | HRH1CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912941-A1 | NOVEL PIPERIDINE DERIVATIVES | AstraZeneca AB (SE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007011293-A1 | NOVEL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-01-25 | — | — | WO | disclosed |