Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 18/20 | 0.55 |
| ▸ | HRH1 | P35367 | 3/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417829 | 0.83 | SSTR5 (0.56) | SSTR5HRH1HTR2B | |
| SCHEMBL1877891 | 0.83 | SSTR5 (0.56) | SSTR5HRH1HTR2B | |
| SCHEMBL3571334 | 0.81 | SSTR5 (0.81) | SSTR5HRH1HTR2B | |
| SCHEMBL3773110 | 0.81 | SSTR5 (0.55) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL1878733 | 0.80 | SSTR5 (0.54) | SSTR5HRH1HTR2B | |
| SCHEMBL3780355 | 0.78 | SSTR5 (0.50) | SSTR5HRH1HTR2B | |
| SCHEMBL1877472 | 0.78 | SSTR5 (0.50) | SSTR5HRH1HTR2B | |
| SCHEMBL1874565 | 0.77 | SSTR5 (0.53) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL1748438 | 0.77 | SSTR5 (0.51) | SSTR5HRH1HTR2BKCNH2 | |
| SCHEMBL1748498 | 0.77 | SSTR5 (0.50) | SSTR5HRH1HTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306116-A1 | ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES | HOFFMANN-LA ROCHE, INC. | 2008-12-11 | — | — | US | claimed |
| US-20080306116-A1 | ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES | HOFFMANN-LA ROCHE, INC. | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306116-A1 | ARYLOXAZOLE, ARYLOXADIAZOLE AND BENZIMIDAZOLE DERIVATIVES | SSTR5, NPY5R, SSTR3 | SSTR5 1/4885HRH1 207/4885HTR2B 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.