SCHEMBL5006858

SCHEMBL5006858

CC(=O)NC1N=NC(=S)S1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5006859 0.58 ATM (0.32) ALDH1A1KDM4ECA1CA2CA9
SCHEMBL8278668 0.49
SCHEMBL1900325 0.49 ATM (0.62) ALDH1A1KDM4EALOX15CA1CA2
SCHEMBL15190542 0.49
SCHEMBL1901754 0.49 PSEN1 (0.45) ALDH1A1KDM4ECA2
SCHEMBL13165905 0.49 ATM (0.62) ALDH1A1KDM4EALOX15CA1CA2
SCHEMBL18231415 0.49
SCHEMBL1896872 0.49 SMN1; SMN2 (0.48) ALDH1A1KDM4ECA2
SCHEMBL21424044 0.49 ATM (0.62) ALDH1A1KDM4EALOX15CA1CA2
SCHEMBL284342 0.49 ATM (0.56) ALDH1A1KDM4EMAPTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4062909-A1 CARBONIC ANHYDRASE 1 (CA1) INHIBITORS FOR THE TREATMENT OR PREVENTION OF MYELOPROLIFERATIVE DISORDERS AND OTHER HEMATOPOIETIC MALIGNANCIES, AND AS BIOMARKER OF MYELOPROLIFERATIVE DISORDERS AND OTHER HEMATOPOIETIC MALIGNANCIES Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2022-09-28 EP disclosed
US-7358038-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2008-04-15 US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
EP-1380890-B1 High speed thermally developable imaging materials and methods of using the same EASTMAN KODAK CO (US) 2007-01-17 EP disclosed
US-7157214-B2 High-speed thermally developable imaging materials EASTMAN KODAK COMPANY (US) 2007-01-02 US disclosed
US-7115358-B2 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. (JP) 2006-10-03 US disclosed
US-7105283-B2 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. (JP) 2006-09-12 US disclosed
US-20060177782-A1 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2006-08-10 US disclosed
US-20050266361-A1 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. 2005-12-01 US disclosed
US-20050244763-A1 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. (JP) 2005-11-03 US disclosed
US-20050214702-A1 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. 2005-09-29 US disclosed
US-20050208437-A1 Black and white photothermographic material and image forming method FUJI PHOTO FILM CO., LTD. 2005-09-22 US disclosed
US-20050069828-A1 High-speed thermally developable imaging materials EASTMAN KODAK COMPANY 2005-03-31 US disclosed
US-6844145-B2 High-speed thermally developable imaging materials and methods of using same EASTMAN KODAK COMPANY (US) 2005-01-18 US disclosed
US-20040009438-A1 High-speed thermally developable imaging materials and methods of using same EASTMAN KODAK COMPANY 2004-01-15 US disclosed
EP-1380887-A1 X-radiation sensitive aqueous-based photothermographic materials and methods of using same EASTMAN KODAK COMPANY (US) 2004-01-14 EP disclosed
EP-1380890-A1 High speed thermally developable imaging materials and methods of using the same EASTMAN KODAK COMPANY (US) 2004-01-14 EP disclosed
US-6576410-B1 Black-and-white photothermographic emulsion EASTMAN KODAK COMPANY 2003-06-10 US disclosed
US-6573033-B1 Photosensitive silver halide grains, nonphotosensitive source of reducible silver ions, reducing agent and phosphor EASTMAN KODAK COMPANY 2003-06-03 US disclosed
US-4034090-A ANTIBACTERIAL RHONE-POULENC INDUSTRIES (FR) 1977-07-05 US disclosed