Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 1.00 |
| ▸ | PPARA | Q07869 | 16/20 | 0.84 |
| ▸ | PPARD | Q03181 | 14/20 | 0.84 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5009219 | 0.91 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4063141 | 0.87 | PPARA (1.00) | PPARGPPARAPPARDPLA2G4A | |
| SCHEMBL5008655 | 0.86 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4231268 | 0.86 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL5011219 | 0.81 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4055034 | 0.80 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL4232687 | 0.80 | PPARD (0.66) | PPARGPPARAPPARDPLA2G4A | |
| SCHEMBL5012486 | 0.78 | PPARG (1.00) | PPARGPPARAPPARD | |
| SCHEMBL6109174 | 0.78 | PPARG (0.64) | PPARGPPARAPPARDPLA2G4A | |
| SCHEMBL18644984 | 0.78 | PPARG (0.87) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| US-7449478-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-11-11 | — | — | US | disclosed |
| US-20050124675-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124675-A1 | Indole compounds | PPARG, PPARD, PPARA | PPARG 1/4885PPARA 3/4885PPARD 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.