Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.55 |
| ▸ | F3 | P13726 | 20/20 | 0.55 |
| ▸ | F10 | P00742 | 16/20 | 0.55 |
| ▸ | F2 | P00734 | 15/20 | 0.55 |
| ▸ | F11 | P03951 | 12/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5009038 | 0.97 | F7 (0.56) | F7F3F10F2F11 | |
| SCHEMBL5009099 | 0.93 | F7 (0.64) | F7F3F10F2F11 | |
| SCHEMBL4611942 | 0.90 | F7 (0.62) | F7F3F10F2F11 | |
| SCHEMBL4999339 | 0.88 | F7 (0.55) | F7F3F10F2F11 | |
| SCHEMBL5000126 | 0.88 | F7 (0.57) | F7F3F10F2F11 | |
| SCHEMBL4612467 | 0.87 | F7 (0.55) | F7F3F10F2F11 | |
| SCHEMBL5003304 | 0.87 | F7 (0.55) | F7F3F10F2F11 | |
| SCHEMBL2852885 | 0.87 | F7 (0.66) | F7F3F10F2F11 | |
| SCHEMBL5009067 | 0.87 | F7 (0.56) | F7F3F10F2F11 | |
| SCHEMBL5003585 | 0.86 | F7 (0.53) | F7F3F10F2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456195-B2 | Phenylglycinamide and pyridylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-11-25 | — | — | US | disclosed |